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Exam 3: NURS5334/ NURS 5334 (Latest 2024/ 2025 Update) Advanced Pharmacology for Nurse Practitioners Guide| Qs & As| 100% Correct| Grade A R204,43   Add to cart
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Exam 3: NURS5334/ NURS 5334 (Latest 2024/ 2025 Update) Advanced Pharmacology for Nurse Practitioners Guide| Qs & As| 100% Correct| Grade A
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Exam 3: NURS5334/ NURS 5334 (Latest 2024/ 2025 Update) Advanced Pharmacology for Nurse Practitioners Guide| Qs & As| 100% Correct| Grade A Q: How does metformin work? Answer:: o Inhibits glucose production in the livero Reduces glucose absorption in the guto Sensitizes insulin receptors ...

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  • November 1, 2024
  • 50
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • nurs5334 nurs 5334nurs
  • nurs5334 nurs 5334nurs5334 nurs 5334 final exam
  • nurs5334 nurs 5334nurs5334 nurs 5334 exam
  • nurs5334 nurs 5334nurs5334 nurs 5334 exam 1
  • nurs5334 nurs 5334nurs5334 nurs 5334 exam 2

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Examl3:lNURS5334/lNURSl5334l(Latest
lUpdate)lAdvancedlPharmacologylforlNursel
PractitionerslGuide|lQsl&lAs|l100%lCorrect|
lGradelA

Q:lHowldoeslmetforminlwork?

Answer::
olInhibitslglucoselproductionlinlthelliverolReduceslglucoselabsorptionlinlthelgutolSensitizeslins
ulinlreceptorslinltargetltissuesl(fatlandlskeletallmuscle)lthuslincrease
glucoseluptakelandlresponseltolwhateverlinsulinlislavailable




Q:lMetforminlWhatlarelsideleffects?lBBlwarning?

Answer::
olGIleffects—diarrhea
olLacticlacidosis




Q:lHowldoeslalcoholleffect?

Answer::
Inhibitslthelbreakdownlofllacticlacid




Q:lWhatlareltheltherapeuticluseslotherlthanlDM?

Answer::

,olGestationalldiabetes
olPCOS




Q:lSulfonylureas

Answer::
olFirstlgeneration
lChlorpropamidel[Diabinese]
lTolazamidel[Tolinase]
lTolbutaminel[Orinase]

olSecondlGeneration:
lGlyburidel[Diabeta,lGlynase,lMicronase]lwithlmetforminl[Glucovance]
lGlypizidel(Glucotrol,lGlucotrollXL);lwithlmetforminl[metaglip])
lGlimepiridel(Amaryl;lwithlmetforminl[AmaryllM],lwithlpioglitazonel[Duetact]
withlrosiglitazonel[Avandaryl]




Q:lMOA?
~~~~~~~~~~~~
Mainlsideleffect?


Answer::
Promotelinsulinlrelease
~~~~~~~~
lHypoglycemia
lWeightlgain




Q:lHowldoeslcimetidineleffect?lBetalblocker?

Answer::
Cimetidine—intensifieslthelresponse
lBetalblockers—diminishlthelbenefitslbylsuppressinglthelinsulinlrelease

,Q:lMeglitinidesl(RepaglinidelandlNateglinide)

Answer::
olMOA—stimulatelpancreaticlinsulinlrelease
olDrug/Druglinteraction—gemfibrozil




Q:lThiazolidinedionesl(glitazones)

Answer::
Reducelglucosellevelslprimarilylbyldecreasinglinsulinlresistance
olOnlylindicationlisltypel2ldiabetes,lmainlylaslanladd-onltolmetformin
olRosiglitazonel[Avandia]:lRestrictedluse
olPioglitazonel[Actos]
olCanltheylbelusedlinlpatientlwithlCHF?
lNo




Q:lAlpha-glucosidaselinhibitorsl(AcarboselorlPrecose;lMiglitoll(glyset))
~~~~~~~~~~~~~~~~~~~~
Whatlraceslareltheselmoreleffectivelin?


Answer::
LatinoslandlAfricanlAmericans




Q:lDPP-4linhibitorsl(gliptins)

Answer::
MOA—promotelglycemiclcontrollbylenhancinglthelactionsloflthelincretinlhormonesland
theylstimulatelglucoseldependentlreleaseloflinsulin
lSuppresslyourlpost-prandiallreleaseloflglucagon

, Q:lWhatlislthel%loflA1Clreduction?

Answer::
0.5%




Q:lHowldoeslcolesevelamlworklinltreatmentloflDM?lBromocriptine?

Answer::
Colesevelam—bilelacidlsequestrantlusedltollowerlcholesterollandlhelpsllowerlblood
glucose
lManylwithldiabeteslalsolhavelhighlcholesterollsol2lbirds-1lstone
olBromocriptine—adjunctltoldietlandlexercisel(0.5%lreduction)




Q:lInjectables:
olAmylinlmemetics?


Answer::
Pramlintide
lSideleffects—hypoglycemialwhenlusedlwithlinsulin
lDrug/Drug—insulin
olGLP-1lreceptorlagonistsl(orlincretinlmimetics)
lCanlcauselmedullarylthyroidlcancer




Q:lWhatlisltreatmentlofldiabeticlketoacidosisl(DKA)?lHypoglycemia?

Answer::
olInsulinlreplacement,lreverselacidosislwithlbicarbonate,lreplacelwater,lsodium,
potassium,lnormalizelglucosellevels

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