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ASCP- Clinical Chemistry QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES 2025/2026 VERIFIED ANSWERS) |ALREADY GRADED A+ R245,77
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ASCP- Clinical Chemistry QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES 2025/2026 VERIFIED ANSWERS) |ALREADY GRADED A+
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ASCP- Clinical Chemistry QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES 2025/2026 VERIFIED ANSWERS) |ALREADY GRADED A+

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  • November 14, 2024
  • 6
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • ascp certification
  • saturation transferrin saturation ans serum
  • albumin ranges if dehydrated ans increased aldos
  • increased in acute pancreatitis and different bell

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  • ASCP CERTIFICATION
  • ASCP CERTIFICATION

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ASCP- Clinical Chemistry

% saturation (transferrin saturation) - ANS-Serum iron/ TIBC x100
Increased in iron overdose, sideroblastic anemia.
Decreased in iron deficiency anemia
Acid phosphatase (ACP) - ANS-Old marker for prostate cancer. PSA is now used (extra
specific).
ACTH - ANS-adrenocorticotropic hormone- stimulates adrenal cortex to secrete CORTISOL
ACTH is expanded in which sickness? - ANS-Cushings disease
Acute pancreatitis enzymes - ANS-Amylase and lipase
ADH (antidiuretic hormone) - ANS-Regulates the reabsorption of water into the renal tubules.
Release stimulated by means of extended osmolality, reduced blood volume or blood strain.
Alanine aminotransferase (ALT) - ANS-Increased in liver sickness.
More precise for liver sickness than AST.
Marked boom in hepatitis.
In RBCs also.
Albumin ranges if dehydrated - ANS-Increased
Aldosterone - ANS-Regulates reabsorption of Sodium in renal tubules.
Increased stages purpose hypertension due to water and sodium retention.
Alkaline phosphatase (ALP) - ANS-Increased in liver obstruction & bone disorder.
Alkaptonuria - ANS-Deficiency of enzyme wished in metabolism of phenylalanine & tyrosine.
Causes of buildup of acid.
Ammonia - ANS-Produced in GI tract, high tiers are neurotoxic.
SAMPLE NEEDS TO BE CHILLED and analyzed asap.
Increased in liver ailment, Reye's syndrome.
Amylase - ANS-Breaks down starch to easy sugars.
Increased in acute pancreatitis and different belly problems.
Aspartate aminotransferase (AST) - ANS-Increased in liver sickness (particularly hepatitis),
myocardial infarction, and muscular dystrophy.
Biliary obstruction ends in an boom in which kind of bilirubin? - ANS-Unconjugated (indirect)
bilirubin
Biliary tract obstruction enzymes - ANS-ALP, GGT
Biuret method depends at the presence of what?- (detection of overall protein ranges) -
ANS-Amount of PEPTIDE BONDS
Bone disease enzymes - ANS-ALP
BUN - ANS-Synthesized by way of liver from ammonia, excreted through kidneys.
Increased levels in kidney sickness
Calcium (Ca2+) - ANS-most abundant mineral inside the frame.
99% in the bones.
REGULATED BY PTH, nutrition D, and calcitonin.
Affected by using pH and temp.

, Cardiac ailment enzymes - ANS-CK-MB
Catecholamines - ANS-Hormones made by adrenal glands (on top of kidneys) at some point of
pressure.
Ex.) dopamine, epinephrine, norepinephrine
Chloride (Cl-) - ANS-Major extracellular anion.
Helps maintain osmolality, blood volume, electric powered neutrality.
PASSIVELY FOLLOWS Na+
Components of Spectrophotometry (in order) - ANS-Light source- monochromator- cuvette-
photodetector- readout
Cortisol - ANS-Regulated by means of ACTH. Diurnal variant (maximum in AM).
Increased in cushing's syndrome.
Decreased in addison's sickness.
Cortisol & epinephrine - ANS-Stress hormone
Insulin antagonist- stimulates glucose manufacturing
Creatine Kinase (CK) - ANS-Most sensitive enzyme for skeletal muscle sickness.
Need heparin tube pattern.
Increased in AMI and muscular dystrophy.
Creatinine - ANS-waste product of muscle metabolism
Cystinuria - ANS-Increased excretion of cystine because of illness in renal reabsorption.
Leads to routine kidney stones
Decreased CO2 - ANS-Metabolic acidosis (compensated respiration alkalosis)
Disease characterized with the aid of extended blood glucose, >40 years old, weight problems,
NO KETOACIDOSIS, no ketones or glucose in urine - ANS-Type 2 diabetes mellitus
(non-insulin established)
Diurnal variant - ANS-Changes in awareness of an analyte based totally on the time of the day
(measured at day vs. Night time)
Does bilirubin sample want to be blanketed from light? - ANS-YES
Ferritin - ANS-Most commonplace form of iron storage, hard estimate of body iron content.
Fluorometry additives (in order) - ANS-Light supply- primary monochromator- cuvette-
secondary monochromator- detector- readout
FSH - ANS-Regulates sperm & egg manufacturing.
Sharp increase simply before ovulation
Gamma-glutamyl transferase (GGT) - ANS-Most touchy enzyme for all varieties of liver disorder.
High in chronic alcoholism (used to screen alcohol ranges).
Highest stages w/ obstructive problems.
Glucose - ANS-main supply of cell energy. Levels lower if sample sits at RT.
Glucose-6-phosphate dehydrogenase (G6PD) - ANS-An enzyme that aids inside the proper
functioning of red blood cells.
Deficiency leads to hemolytic anemia.
Growth hormone - ANS-Regulates protein synthesis, cellular boom, & department.
Increase in gigantism.
HDL - ANS-"suitable fat"- levels must be >60 mg/dL
Hepatocellular sickness enzymes - ANS-AST, ALT, LD
Homocystinuria - ANS-Deficiency of enzyme needed for metabolism of methionine.

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