, Interphase........................................................................................................................................21
DNA supercoiling.............................................................................................................................21
Mitosis.............................................................................................................................................22
Cytokinesis.......................................................................................................................................23
Mitotic index....................................................................................................................................23
Cyclins..............................................................................................................................................24
Cancer development........................................................................................................................25
1. CELL INTRODUCTION
Cell theory
o The cell is the smallest unit of life.
2
, o All living organisms are composed of cells.
o All cells come from pre-existing cells.
Exceptions to cell theory
Striated muscle
o Skeletal muscle fibres fuse together and are larger
(30cm)
o Multiple nuclei surrounded by a single plasma
membrane.
o Doesn’t follow the rule which says cells function as
autonomous units.
Giant algae
o Single celled organism challenged the idea of small and
simple structure.
o Complex structure made up of 3 anatomical parts.
o Challenge the idea larger organisms are made of many
microscopic cells.
Aseptate fungal hyphae
o Challenges idea that a cell is a single unit
o Hyphae are large, many nuclei
o Continuous cytoplasm
o No division between cells
Red blood cell
o Don’t have a nucleus
Functions of life
An organism must fulfil all live processes to be considered a living
organism.
o Metabolism (respiration) undertake essential chemical reactions
o Reproduction produce offspring, sexually or asexually
o Sensitivity responsive to internal and external stimuli
o Homeostasis maintain a stable internal environment
(temperature in humans)
o Excretion remove waste products
o Nutrition exchange materials and gases with the environment
o Growth can move and change shape and size
Application
Paramecium (heterotroph)
3
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