FPGEE Exam Questions with Correct Answers

FPGEE Exam Questions with Correct Answers W/O emulation is good for produce? - Answer-Lotions,liniments O/W emulations is good for produce? - Answer-Oral emulations for taste Micro emulations is good for produce? - Answer-Solubilization, 10-200 nm Nanoparticle emulsions is good for produce? - Answer-Globulin and toxoid, IGG and tetanus toxoid W/O/W emulations is good for produce? - Answer-Prolong duration of action drug, localize drug in the body, cosmetic Preservatives - Answer-Cetylpyridinium,benzalkonium,thiomersal,cresol,chlorobutanol, phenol,benzyl alcohol, benzoic acid Losartan - Answer-Cozaar, ARB 50 mg per day Hyper kalmia, angioedema Fick's low - Answer-Rate of solution D A ( c2-c1)/L D= Diffusion coefficient A= surface area of solid L= length of stagnant layer Acetone Water Benzene In terms of polarity ? - Answer-Acetone semepolar solvent Water polar solvent Benzene no polar solvent The process of degradation of ionic salt If the solvent is other than water - Answer-Hydration Solvation Pseudo plastic flow - Answer-Shear thinning agent,the viscosity decrease with increase in rate of shear Plastic flow - Answer-Bingham body, has a yield value to break down vanderwalls forces between folucculated particles Dilatant flow - Answer-Shear thicking system, viscosity increase with increase shear rate, suspension with 50% or greater deflocculated small particles Thixotropy - Answer-Gel to sol and reforms to gel Micro emulation - Answer-Between emulation and solvent, combination oil and water make homogeneous and transparent by adding surfactant and cosurfactant, particle size 10-200 nm Lyophilic - Answer-Considerable interaction between disperse phase and dispersion phase, hydrophilic, lipophilic Floculated suspension - Answer-High rate of sedimentation, easily redispersed sediment, clear supernatant region, most acceptable in pharmacy practice Deflocculated suspention - Answer-Slow rate of sedimentation, very difficult to redispersed , cloudy supernatant Stoke's low rate of sedimentation - Answer-V= 2r^2(p2-p1)g 9n Glycolipid - Answer-Fatty acid, galactose, sphingosine Phospholipid - Answer-Fatty acid phosphoric acid,nitrogenous compounds Sterols - Answer-Alcohol structure related to steroid Waxes - Answer-High molecular weight esters Titration method - Answer-Acid base Percipitation Redox Complexation Large anion and large cation Gravimetric methods - Answer-Weighing drugs after separation Weighing a derivative after separation Weighing residue after ignition Spectrometric methods - Answer-Colorimetric UV, IR, NMR, Atomic absorption Fluorimetric emission Electrochemical methods - Answer-Voltammetery Potentiometery Chromatographic - Answer-TLC, HPLC,Gas chromatography Abnormal hemoglobin, hemolytic anemia - Answer-Sickle cell anemia, betathalassemia How abnormal hemoglobin could cause rupture of red blood cells - Answer-It's solubility is low and make crystal