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Inflammatory bowel diseases (IBD) + Colorectal Cancer : recent trends, questions and answers 8,78 €   Añadir al carrito

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Inflammatory bowel diseases (IBD) + Colorectal Cancer : recent trends, questions and answers

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Inflammatory bowel diseases (IBD) + Colorectal Cancer : recent trends, questions and answers Ulcerative Colitis - CORRECT ANSWER - - Affects colon - Bimodal demographic (2nd-3rd and 7th decades) - Remitting/relapsing disease Classification of UC - CORRECT ANSWER - *Classified by extent* - Pro...

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  • 11 de agosto de 2024
  • 7
  • 2024/2025
  • Examen
  • Preguntas y respuestas
  • IBD
  • IBD
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Inflammatory bowel diseases (IBD) + Colorectal Cancer : recent trends, questions and answers

Ulcerative Colitis - CORRECT ANSWER - - Affects colon

- Bimodal demographic (2nd-3rd and 7th decades)

- Remitting/relapsing disease



Classification of UC - CORRECT ANSWER - *Classified by extent*

- Proctitis (just the rectum, always begins here!)

- Left-sided

- Extensive

- Pancolitis (entire colon)



Only 1/3 of pts will have extension of disease over time.



Classification of US - CORRECT ANSWER - *Mild:* less than 4 stools/day, +/- small amount of blood, Mild
anemia

- No fever, normal HR and SED



Moderate: (mix of mild/severe)



*Severe*: More that 6 stools a day + blood and at least one of the following:

- Fever

- HR > 90

- Anemia (< 75% of normal hemoglobin)

- Elevated ESR (>30 mm/hr)

, Macroscopic findings of US - CORRECT ANSWER - - Typically most severe distally ==> gets better
proximally

- Long standing disease = "lead pipe colon" (atrophic and featureless)



Goals of IBD treatment - CORRECT ANSWER - 1. Induce remission

2. Maintain remission



UC treatments - CORRECT ANSWER - 1. Steroids (induction only!!)

2. Oral ASA's - good for maintenance of remission in mild disease

3. Rectal ASA's (good for distal disease)

4. Immunomodulators- take 12-14 days to work (Azathopine can cause pancreatitis)

5. Biologics - induction and maintenance

6. Surgery (CURATIVE in UC)



Colon cancer risk in UC - CORRECT ANSWER - - UC pts are at higher risk of CRC

- start colonoscopy 8-10 years after diagnosis (immediately if also have PSC)

- Surveillance colonoscopy every 1-2 years



- 5 ASA's may reduce risk of CRC



- Crohn's colitis and UC have same cancer risk!



Toxic Megacolon - CORRECT ANSWER - - *Potentially FATAL complication of UC*



*sxs*: abd distension, reduced bowel sounds, pain and constitutional sxs

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