1. What are the stages of cell growth in cancer development
ANS 1. Initiation
2. Promotion
3. Progression
4. Metastasis
2. What happens during Initiation phase during cancer cell growth
ANS normal cells become damaged and leads to development of cancer (Malignant
Transforma- tion)
this is irreversible
3. What happens during the promotion stage during cancer cell g rowth
ANS -re- peat exposure to carcinogen enhances cell growth which leads to mutation
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-enhanced cell growth of cells by promotors (like hormones primarily estrogen)
-period between initiation and growth into a tumor is called a latency period
4. What happens during the progression stage of cancer cell growth
ANS -An increase in the production of malignant cells
-after a tumor reach 1 cm, it already has 1 billion cells
-when it builds its own blood supply it becomes a health problem
5. What happens during the Metastasis stage of cancer cell growth
ANS -move- ment of cells from the primary site and establishing remote colonies
6. Malignant vs. Benign
: Malignant
-Anaplasia-loss of appearance of parent cell
-A larger nuclear- to-cytoplasmic ration
-Specific functions are lost-serve NO purpose
-Loose adherence-loosely bound due to the lack fo fibronectin production
-migration-spreads easily (metastasis)
-Contact inhibition does not occurs
-Rapid or continuous cell division Powered by TCPDF (www.tcpdf.org)
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