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MMSC 490 Final Exam Practice Questions and Answers

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MMSC 490 Final Exam Practice Questions and Answers Which of the following regulates genes by binding directly to transcription proteins? a. Growth hormone b. insulin c. steroid hormones d. epinephrine - Answer ️️ -c. steroid hormones Monomeric G proteins, such as Ras and several elongatio...

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MMSC 490 Final Exam Practice Questions and Answers Which of the following regulates genes by binding directly to transcription proteins? a. Growt h hormone b. insulin c. steroid hormones d. epinephrine - Answer ✔️✔️-c. steroid hormones Monomeric G proteins, such as Ras and several elongation factors, are usually in the active state when a molecule of ____ is bound to them. a. GDP b. GTP c. ADP d. ATP - Answer ✔️✔️-b. GTP The first amino acid of eukaryotic polypeptides is a. the amino acid encoded by the first 5' codon b. valine c. N-formylmethione d. methionine - Answer ✔️✔️-d. methionine the primary function of rRNAs in the ribosome is a. to se rve as a scaffold for the ribosomal proteins b. to assist in the proper positioning of tRNAs along the mRNA template c. to catalyze peptide bond formation d. to assist in the proper folding of ribosomal proteins - Answer ✔️✔️-c. to catalyze peptide bond formation the amount of a protein in a cell is regulated by the rate of a. transcription of its gene b. transcription of its mRNA c. degradation of the protein d. All of the above - Answer ✔️✔️-d. All of the above the first amino acid that initiates the eukaryotic polypeptide is a. any amino acid b. glutamine c. methionine d. N-formylmethionine - Answer ✔️✔️-c. methionine the signal sequence of a protein being translocated into the endoplasmic reticulum is cleaved off by a signal peptidase located a. on the inner surface of the ER membrane b. in the lumen of the ER c. on the amino terminal of the polypeptide being translocated d. in the cytosol - Answer ✔️✔️-a. on the inner surface of the ER membrane prior to N -linked glycosylation of a protein, a complex oligosaccharide is assembled in the endoplasmic reticulum on a lipid carrier called a. a prenyl grouo b. myristic acid c. dolichol phosphate d. phosphatidylinositol - Answer ✔️✔️-c. dolichol phosphate The correc tly folded three -dimensional configuration of a protein is determined primarily by the a. sequence of nucleotides of its gene b. primary sequence of its amino acids c. chaperones with which it interacts d. pathway by which it folds - Answer ✔️✔️-b. primar y sequence of its amino acids what happens to ubiquitin in proteosomes a. it is degraded b. it is released and recycled c. it is phosphorylated d. it has a GTP group added - Answer ✔️✔️-b. it is released and recycled Which of the following processes does not require the assistance of chaperones a. protein transport into the nucleus b. protein transport into the ER c. folding during protein synthesis d. assembly of proteins consisting of multiple polypeptide chains - Answer ✔️✔️-a. protein transport into the nucleus which of the following statements regarding tRNAs is false a. tRNAS are approx 70 -80 bases long and form cloverleaf structure b. all tRNAs have a CCA sequence at their 3' terminus c. tRNAs differ in sequence only at the anticodon d. there are several modified bases present in mature tRNAs - Answer ✔️✔️-c. tRNAs differ in sequence only at the anticodon eukaryotic ribosomes recognize and initially bind to what structure on the mRNA a. A shine dalgarno sequence b. the 7 methyl guanosine cap c. A TATA sequence d. A CCAAT sequence - Answer ✔️✔️-b. the 7 methyl guanosine cap Many chaperones are called heat -shock proteins because they a. are expressed at higher levels after a heat shock than at normal growth condit ions b. causes fever in mammals c. misfold during a heat shock d. denature at high temperatures - Answer ✔️✔️-a. are expressed at higher levels after a heat shock than at normal growth conditions OOcytes store mRNAs with ____ and activate them by ___ a. no cap; addition of a cap b. long poly -A tails, shortening the tails c. short poly -A tails; lengthening the tails d. bound siRNA; removing the siRNA - Answer ✔️✔️-c. short poly -A tails; lengthening the tails E. coli contains about _______ different tRNAs that code for _______ different amino acids.

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