STUVIA
- ✔✔antitubercular drug interactions
-amikacin
-gentamicin
-streptomycin
give only for as long as prescribed can cause kidney damage and hear loss, when giving IV dilute it
and give over 30-60mins, assess for confusion, weakness and sleep or eye disorder -
✔✔aminoglycoside drugs and nursing implications
-amoxicillin (augmentin, moxatag)
shake liquid thoroughly before giving, give moxatag within 1h after meal, dont chew ER tabs, dont
inject penicillin G into blood vessel and use Z track method, aspirate before giving IM dose, dont
interchange amoxicillin and clavulanic acid, penicillin V potassium are higher when taken on empty
stomach but if GI upset occurs take with food - ✔✔penicillin drugs and nursing implications
-azithromycin (zithromax)
-clarithromycin (biaxin)
-erythromycin
consult with provider for pts taking other drugs because these react with many drugs, dont use with
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drugs that may cause prolonged QT intervals, palpitations and angina may occur, take erythromycin
with food or milk, monitor liver enzymes, assess for jaundice - ✔✔macrolide drugs and nursing
implications
-bio statin, nyata
prepare only single dose of powder, shake liquid well, tell pt to take one half of dose in each side of
mouth for several minutes before swallowing, retain dose in mouth for several minutes before
swallowing, may increase glucose in diabetic pts - ✔✔nystatin drugs and nursing implications
-cefaclor
-cefuroxime (ceftin) given IM Z track method, tabs cant be substituted mg for mg, suspension must be
given with food
gram positive coverage and more effective against gram negative bacteria - ✔✔second generation
cephalosporin drugs
-cefazolin given IM Z track method
-cephalexin (keflex)
supplies gram positive coverage - ✔✔first generation cephalosporin drugs
-cefdinir (omnicef)
,STUVIA
-ceftriaxone given IM Z track method, IV cant be given with ringer lactate or IV push, must be infused
over 30 mins
more potent against gram negative bacteria - ✔✔third generation cephalosporin drugs
-chloroquine/Aralen (causes personality changes, anxiety, depression)
-primaquine (causes hemolytic anemia, leukopenia, dysrhythmias)
take with food, observe pt for corneal opacities, notify provider of visual changes, can cause
retinopathy, may worsen psoriasis, notify provider of personality changes, increases risk of seizures,
digoxin levels and digoxin toxicity, monitor and report fatigue, dark urine, feeling of fullness in
stomach, can impair and enlarge liver - ✔✔antimalarial drugs and nursing implications
-ciprofloxacin (cipro)
-levofloxacin (levaquin)
give with food but no dairy, dont use in children under 18 years old, stop drug and notify provider if
joint pain or inflammation occurs, IV doses mixed and given over 60-90mins, increase fluids, avoid
sunlight, check glucose levels for diabetic pts, notify provider if tingling, numbness, tendonitis or pain
occurs - ✔✔fluoroquinolone drugs and nursing implications
-cream, powder, ointment, solution, suppository
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dont use intravaginally for longer then 7 days, notify provider if no improvement of symptoms after 3
days, topical tx for ringworm and athletes foot shouldnt exceed 4wks, application for jock itch shouldnt
exceed 2wks - ✔✔miconazole drugs and nursing implications
-doxycycline
-minocycline hydrochloride (minocin)
-tetracycline
wear sunscreen and protective clothing, take 1h before meal or drinking milk or 2h after eating, ask pt
if using retinoids for acne because it can cause rise in ICP - ✔✔tetracycline drugs and nursing
implications
-fluconazole (diflucan) vaginal
-ketoconazole (nizoral, extina) topical or oral can cause photosensitivity
monitor for rash, redness and blistering and notify provider, can cause steven johnson syndrome,
monitor glucose levels when taking antidiabetics, monitor BUN, creat and liver function studies, report
jaundice, light stools and dark urine, mix IV fluconazole and give no faster then 200mg/h, take pulse
daily, report pulse >100 or <60, take ketoconazole with acidic beverage (cola), tell sexually active
women to use birth control because it can cause birth defects , monitor renal and hepatic function -
✔✔azole drugs and nursing implications
, STUVIA
-gris PEG, grifulvin can cause photosensitivity, paresthesia, liver toxicity
take with fatty meal, check for numbness or tingling of feet and report, wear sunscreen and protective
clothing, report rash or hives, report jaundice, light color stools and dark urine, avoid alcohol, tell
sexually active women to use birth control because it can cause birth defects - ✔✔griseofulvin drugs
and nursing implications
-imipenem (primaxin)
-meropenem (merrem)
-ertapenem (invanz)
dont use IM for imipenem or ertapenem, give IM using Z track method, aspirate before IM injection,
monitor for confusion and seizure, use with ganciclovir causes seizures, monitor when taking with
warfarin for bleeding abnormalities and changes in INR levels, when used with other antibiotics
monitor urine and lab tests closely - ✔✔carbapenem drugs and nursing implications
-isoniazid (INH)
avoid antacids and alcohol, take on empty stomach or 1hr before or 2hrs after meal, causes
peripheral neuropathy and psychological changes, take daily B vitamin, report jaundice, dark urine,
bruising and bleeding, only use IM if oral route is not practical - ✔✔isonizid drugs and nursing
implications
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-kanamycin (kantrex)
-capreomycin (capastat)
length of tx and dose vary depending on age, weight and resistance patterns, causes nephrotoxicity
and ototoxicity, administer audiometry test, monitor BUN, creat and CBC, causes respiratory
depression and paralysis with IV use, causes vitamin B deficiency, interferes with metabolism and
absorption, obtain kanamycin levels, kanamycin has fetal risk dont use during pregnancy -
✔✔aminoglycoside drugs and nursing implications
-ketoconazole/Nizoral: broad spectrum, treats thrush, candidiasis, histoplasmosis
-nystatin/Mycostatin: antibiotic, treats intestinal, vaginal and oral fungal infections, shake thoroughly
before use
-amphotericin B/Amphotec: systemic drug
-Griseofulvin: activity decreased with barbiturates, causes photosensitivity
-metronidazole/Flagyl: used for mixed fungal and bacterial or protozoa infections, interacts with
alcohol - ✔✔common antifungal meds
-metronidazole/Flagyl
-iodoquinol/Yodoxin (take after meals or with food)
