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Rnc Pharmacology Questions And Answers With Verified Solutions Already Passed!!!
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Rnc Pharmacology Questions AndAnswers With Verified Solutions Already
Passed!!!
pharmacodynamics - ANSWER✔✔study of how chemicals produce their biologic
effect on living tissue
pharmacokinetics - ANSWER✔✔mathematical relationship between a drug
dosage and resulting serum concentration
drug-receptor affinity - ANSWER✔✔principle that drugs act by binding with
receptor sites
drug-receptor specifity - ANSWER✔✔receptor binds only with certain drugs
drug-receptor binding - ANSWER✔✔ability for drug to bind with receptor site
plays a role in determining response. types: regulation of gene expression, change
cell membrane permeability, increasing intracellular second messengers
agonist - ANSWER✔✔drugs stimulates receptor to produce effect
antagonist - ANSWER✔✔prevents receptor binding to produce results
dose-response relationship - ANSWER✔✔individuals in a population receiving a
drug have varied response to the same dose (i.e. narcan). sensitivity, tolerance,
tachyphylaxis (rapid decline of drug response w/o changing drug dose)
, desired effects - ANSWER✔✔expected therapeutic response
adverse effect - ANSWER✔✔harmful, unintended effect of a medication
administered at normal dosage
toxicity - ANSWER✔✔exposure to toxic amounts of a medication that does not
cause adverse effects in smaller amounts
neonatal implications for drugs - ANSWER✔✔- steroids (systemic): impaired
linear growth
- metoclopramide: acute dystonic reactions (reglan)
- opioids: respiratory depression
- chloral hydrate, phenobarb, benadryl: paradoxical hyperactivity
- ampicillin: non-allergic rash on trunk
bioavailability - ANSWER✔✔- extent of absorption
- the portion of the dose that reaches the systemic circulation
drug routes - ANSWER✔✔- oral
- IV
- IM/SQ
- rectal
- topical
- inhalation
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