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PCB 3233 Exam 2 questions with 100% correct answers graded A+
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PCB 3233 Exam 2 questions with 100% correct answers graded A+
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PCB 3233 Exam 2What are two cells that use receptors to distinguish between self and non-self cells? - correct answer
✔✔-Macrophages
-NK Cells
C3b is a ligand for - correct answer ✔✔Macrophage CR1
CR3 & CR4 - correct answer ✔✔Recognize iC3b & other ligands including LPS
Lectins - correct answer ✔✔Carbohydrates-binding proteins
ex: Mannose & glucose receptors
Scavenger Receptors - correct answer ✔✔Prefer molecules that are negatively charged like nucleic acids,
LPS.
Phagocytic Receptors - correct answer ✔✔Bind directly to microbial surface components
What do surface receptors promote? - correct answer ✔✔Phagocytosis
PRR's bind to - correct answer ✔✔PAMPs on pathogens
Receptors that detect microbial products signal what? - correct answer ✔✔-Macrophage activation
-Cytokine Secretion
Toll-Like Receptors (TLR) - correct answer ✔✔-10 receptors
-Has specificities for several microbial products
, TLR-4 - correct answer ✔✔-Senses LPS
-Found on macrophages
What can LPS cause? - correct answer ✔✔Septic Shock
What is LPS known for being? - correct answer ✔✔Endotoxin
What is local accumulation of fluid accompanied by? - correct answer ✔✔Swelling, redness, heat, & pain
What does increased dilation cause? - correct answer ✔✔Reduced blood flow
Complement receptors 3&4 (Mac-1, CD11b, CD8) target what? - correct answer ✔✔Bacteria & Fungi
CD14 binds to what? - correct answer ✔✔-LPS
-Peptidoglycan
What does IL-8 (CXCL-8) do? - correct answer ✔✔Attracts leukocytes (neutrophils) to the site of
infection/damage
What are your proinflammatory cytokines? - correct answer ✔✔-IL-1Beta
-IL-6
-CXCL8 (IL-8)
-IL-12
-TNF Alpha
What does TLR7 Recognize? - correct answer ✔✔-Ligand: Single stranded viral RNA
-Detects RNA viruses
-Carried by dendritic cells, NK cells, eosinophils, & B-cells
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