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APEA- Orthopedics PHARM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS 2025
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APEA- Orthopedics PHARM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS 2025
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APEA- Orthopedics PHARM QUESTIONS ANDANSWERS WITH COMPLETE SOLUTIONS 2025
Probenecid, used in the treatment of gout, works by:
-decreasing the tubular secretion of uric acid and inhibiting the
secretion of penicillin.
-destroying uric acid crystals in the renal tubular system and slowing the
metabolism of penicillin.
-increasing the urinary excretion of uric acid and inhibiting the secretion
of penicillin.
-promoting the bactericidal activity of penicillin and breaking down uric
acid. - ANSWER increasing the urinary excretion of uric acid and
inhibiting the secretion of penicillin.
Before prescribing Dantrolene (Dantrium), a peripherally-acting muscle
relaxant, obtain a baseline serum:
blood urea nitrogen (BUN).
complete blood count (CBC).
calcium level.
liver function test. - ANSWER Liver function test
Which of the following is NOT a reason to discontinue allopurinol
(Zyloprim)?
Acute gout exacerbation
,Dysuria
Jaundice
Skin rash - ANSWER acute gout exacerbation
Patients should be instructed to take tizanidine (Zanaflex):
daily, not exceeding 16 mg daily.
before bedtime only.
with food only.
consistently fasting or nonfasting. - ANSWER consistently fasting or
nonfasting.
do not switch method of administrations- will change absorption of
drug
The maximum recommended daily dose of acetaminophen (Tylenol) for
the management of pain associated with a clavicular fracture is:
1 gram.
2 grams.
3 grams.
4 grams. - ANSWER 4 grams
Patients should be instructed to avoid abrupt withdrawal of baclofen
(Lioresal) to prevent the occurrence of:
, hypotonia.
urinary retention.
seizures.
hypothermia. - ANSWER seizures
Ketorolac (Toradol), a nonsteroidal anti-inflammatory drug, is:
indicated for short-term treatment of moderate pain.
not known to cause renal insufficiency.
indicated for the treatment of moderate pain in children.
indicated for pain following coronary artery bypass graft surgery. -
ANSWER indicated for short-term treatment of moderate pain.
When corticosteroids are used in combination with nonsteroidal anti-
inflammatory drugs (NSAIDs), patients may develop:
osteoarthritis.
diabetes insipidus.
gastrointestinal bleeding.
hypoglycemia. - ANSWER gastrointestinal bleeding
Patients may develop increased gastrointestinal symptoms and bleeding
because both products diminish the gastroprotective effects of
prostaglandins.
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