WGU D027 Advanced Pathopharmacological Foundations
Pre- Assessment Exam WITH Questions and Verified Answers
100% Graded A+
1. What organ does cystic fibrosis affect?: Affects the pancreas causing secre-
tions into the lungs
2. What is Klinefelter syndrome?: An extra X chromosome for males so exampleXXY
causing female-like qualities
3. What is Turner Syndrome?: females. missing or deformed x chromosome. right
hemisphere dysfunction, hearing loss, ear infection, language and articulation dis-
orders, visual spatial and attentional problems
4. What is beta thalassemia?: a condition in which the synthesis of the beta-globin
chains is decreased or absent. Causes low hemoglobin.
5. Which medication is contraindicated in a patient with Beta Thalassemia?: -
Ferrous Sulfate
6. What drug is used in combination with other agent to treat lymphoid tissue
(leukemia). Directly toxic to lymphoid tissues Selective estrogen receptor
modulators (SERM) - for hormone receptor positive and advanced breast cancer.
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,(Tomaxafin - reduces risk and recurrence risk): Glucocorticoids
7. What is the normal ejection fraction?: 55-60%. Less than 50% is BAD
8. Is an ejection fraction of 50% reduced or preserved?: Preserved
9. What are symptoms of left sided heart failure?: Think PULMONARY. JVD,FVO,
rails, S3 murmurs. Number one cause of right sided heart failure!
10. What are symptoms of right sided heart failure?: Think peripheral vascular.
Lower extremity edema, abdominal distension.
11. What is the gold standard lab test for heart failure?: BNP. Heart failure is a
result greater than 100
12. What heart disease is worse with exertion?: Ischemic heart disease becausethe
demand requirements are higher.
13. What should you assess before giving Digoxin?: Apical pulse
14. How should Warfarin be started?: Start initial dose at half to monitor the effects
15. What causes the destruction of alveolar walls? Air goes in but can't get out
which leads to hyperinflation: Emphysema
16. What causes excess mucus production and smooth muscle hypertrophy?-
: Bronchitis
17. What is a chronic inflammatory obstruction of bronchi?: Asthma, Triggers
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, cause mucus to clog bronchial tubes.
18. What causes an overbite and buffalo hump?: Endocrine disorder called
acromegaly (overproduction of growth hormone)
19. What causes Addison's disease?: Decreased glucocorticoid (due to autoim-
mune destruction of adrenal cortex)
20. What causes Cushing's syndrome?: excess cortisol
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