BB 451: Nucleotide questions with
verified answers graded A+ passed
Deoxyribonucleotides are formed - correct answer ✔✔As diphosphates by
reduction of ribonucleoside diphosphates
In nucleoside anabolism, the nucleosides get atoms from amino acids, including
aspartate and glutamine. But purines also get atoms from this source that
pyrimidines don't: - correct answer ✔✔Glycine
Fluorouracil is an effective inhibitor of - correct answer ✔✔thymidylate synthase
Ribonucleotide reductase uses which of the following cofactors? - correct answer
✔✔thioredoxin
The conversion of uracil to thymine requires a one-carbon transfer with - correct
answer ✔✔tetrahydrofolate as the donor
Which best describes the synthesis of purine nucleotides? - correct answer
✔✔The basic ring structure, inosine, is synthesized stepwise on ribose. This is
then modified to produce either GMP or AMP.
One way in which the anabolism of pyrimidine nucleotides differs from that of
purine nucleotides is that - correct answer ✔✔The pyrimidine ring is assembled
verified answers graded A+ passed
Deoxyribonucleotides are formed - correct answer ✔✔As diphosphates by
reduction of ribonucleoside diphosphates
In nucleoside anabolism, the nucleosides get atoms from amino acids, including
aspartate and glutamine. But purines also get atoms from this source that
pyrimidines don't: - correct answer ✔✔Glycine
Fluorouracil is an effective inhibitor of - correct answer ✔✔thymidylate synthase
Ribonucleotide reductase uses which of the following cofactors? - correct answer
✔✔thioredoxin
The conversion of uracil to thymine requires a one-carbon transfer with - correct
answer ✔✔tetrahydrofolate as the donor
Which best describes the synthesis of purine nucleotides? - correct answer
✔✔The basic ring structure, inosine, is synthesized stepwise on ribose. This is
then modified to produce either GMP or AMP.
One way in which the anabolism of pyrimidine nucleotides differs from that of
purine nucleotides is that - correct answer ✔✔The pyrimidine ring is assembled
