NURS 5315: Adv Patho Exam 2 Set 1 Questions & Answers (100% Correct)

NURS 5315: Adv Patho Exam 2 Set 1 Questions & Answers (100% Correct) NURS 5315: Adv Patho Exam 2 Set 1 Questions & Answers (100% Correct) First 5 steps in the inflammatory process - ANSWER - 1. mast cell degranulation 2. activation of coagulation cascade 3. activation of kinin cascade 4. release of chemotactic factors 5.Activation of the complement cascade Role/function in the inflammatory process: Complement - ANSWER - Form the membrane attack complex bacterial lysis vasodilation Increased vascular permeability triggers mast cell degranulation chemotaxis opsonization - opsonins tag foreign pathogens for elimination by phagocytes Role/function in the inflammatory process: kinin - ANSWER - turned into bradykinin which is responsible for pain, chemotaxis and Increased vascular permeability and vasodilation Role/function in the inflammatory process: Coagulation cascade - ANSWER - plays role in activating the kinin system Factor XII (Hagemon factor) activates kinin and forms a fibrin mesh to stop bleeding and trap microorganisms Role/function in the inflammatory process: chemotactic factors - ANSWER - once released attract neutrophils, eosinophils and monocytes for phagocytosis Role/function in the inflammatory process: Neutrophils - ANSWER - show up at the site of injury in 6-8 hours Neutrophils express and release cytokines, which in turn amplify inflammatory reactions by several other cell types. In addition to recruiting and activating other cells of the immune system, neutrophils play a key role in the front-line defense against invading pathogens. Role/function in the inflammatory process: monocytes - ANSWER - Show up in 1-7 days become macrophages present antigens to the CD4 cell which leads to Tcell immunity which leads to B cell immunity Releases IL1, IL6, TNF and growth factors