ASCP Exam 1 Questions & Answers
2023/2024
The two larger mucus glands with ducts opening near the vaginal orifice are: - ANSWER-Bartholin's
glands
The presence of benign appearing columnar epithelium in a lateral vaginal wall scraping is most
consistent with a prior exposure to: - ANSWER-Diethylstilbesterol
A culdocentesis from a 35 yr old woman complaining of dysmenorrhea reveals tightly packed clusters of
small uniform cells with uniform nuclei. These are most consistent with: - ANSWER-Endometriosis
A cervical smear from a 24 yr old pregnant women contains sheets of cells with:
-enlarged hyperchromatic nuclei
-prominent nucleoli
-scattered mitotic figures
-abundant, pulled out, cyanophilic cytoplasm - ANSWER-Reparative Epithelium
A cervicovaginal smear reveals a palisade grouping of cells with eccentric nuclei. Beneath these cells is a
single row of cells with indistinct cytoplasmic boundaries. The lower group of cells most likely
represents: - ANSWER-Reserve cells
Macronucleoli in cervicovaginal smears are most prominent in: - ANSWER-Repair
A cervical smear contained sheets of cells with:
-eccentric, crowded nuclei
-homogeneous, cyanophilic cytoplasm
-numerous, eosinophilic, hair like structures at the apical surface - ANSWER-Tubal metaplasia
, A cervicovaginal smear from a 22 yr old pregnant woman revealed several multinucleated cells with:
-cyanophilic cytoplasm with tails
-overlapping nuclei
-coarse chromatin - ANSWER-Syncytiotrophoblasts
Several clusters of cells were seen in a routine cervical smear from a 45 yr old woman on day 8 of her
menstrual cycle. These clusters were made up of two different cell populations. The inner core was
comprised of small, dark tightly packed cells, while the outer rim resembled low cuboidal epithelium.
Findings are consistent with: - ANSWER-Exodus pattern
During the last stage in the normal maturation process of the squamous epithelium of the cervix and
vagina, the cells undergo: - ANSWER-Nuclear pyknosis
Endometrial stromal cells in the cervical smears may be difficult to distinguish from: - ANSWER-Small
histiocytes
the normal endocervical canal is predominantly lined with: - ANSWER-Simple columnar epithelium
A cervicovaginal smear contained:
-numerous ovoid, cyanophilic bodies
-elliptical shaped nuclei
-eosinophilic cytoplasmic granules
Associated with what inflammatory pattern? - ANSWER-Acute
A multinucleated cell with nuclei arranged single file around the periphery of the cytoplasm and a finely
granular chromatin pattern would be most consistent with: - ANSWER-Granulomatous inflammation
A smear from a 65 yr old postmenopausal woman contains many eosinophilic parabasal like cells with
small pyknotic nuclei. The most likely diagnosis is: - ANSWER-Atrophic vaginitis
2023/2024
The two larger mucus glands with ducts opening near the vaginal orifice are: - ANSWER-Bartholin's
glands
The presence of benign appearing columnar epithelium in a lateral vaginal wall scraping is most
consistent with a prior exposure to: - ANSWER-Diethylstilbesterol
A culdocentesis from a 35 yr old woman complaining of dysmenorrhea reveals tightly packed clusters of
small uniform cells with uniform nuclei. These are most consistent with: - ANSWER-Endometriosis
A cervical smear from a 24 yr old pregnant women contains sheets of cells with:
-enlarged hyperchromatic nuclei
-prominent nucleoli
-scattered mitotic figures
-abundant, pulled out, cyanophilic cytoplasm - ANSWER-Reparative Epithelium
A cervicovaginal smear reveals a palisade grouping of cells with eccentric nuclei. Beneath these cells is a
single row of cells with indistinct cytoplasmic boundaries. The lower group of cells most likely
represents: - ANSWER-Reserve cells
Macronucleoli in cervicovaginal smears are most prominent in: - ANSWER-Repair
A cervical smear contained sheets of cells with:
-eccentric, crowded nuclei
-homogeneous, cyanophilic cytoplasm
-numerous, eosinophilic, hair like structures at the apical surface - ANSWER-Tubal metaplasia
, A cervicovaginal smear from a 22 yr old pregnant woman revealed several multinucleated cells with:
-cyanophilic cytoplasm with tails
-overlapping nuclei
-coarse chromatin - ANSWER-Syncytiotrophoblasts
Several clusters of cells were seen in a routine cervical smear from a 45 yr old woman on day 8 of her
menstrual cycle. These clusters were made up of two different cell populations. The inner core was
comprised of small, dark tightly packed cells, while the outer rim resembled low cuboidal epithelium.
Findings are consistent with: - ANSWER-Exodus pattern
During the last stage in the normal maturation process of the squamous epithelium of the cervix and
vagina, the cells undergo: - ANSWER-Nuclear pyknosis
Endometrial stromal cells in the cervical smears may be difficult to distinguish from: - ANSWER-Small
histiocytes
the normal endocervical canal is predominantly lined with: - ANSWER-Simple columnar epithelium
A cervicovaginal smear contained:
-numerous ovoid, cyanophilic bodies
-elliptical shaped nuclei
-eosinophilic cytoplasmic granules
Associated with what inflammatory pattern? - ANSWER-Acute
A multinucleated cell with nuclei arranged single file around the periphery of the cytoplasm and a finely
granular chromatin pattern would be most consistent with: - ANSWER-Granulomatous inflammation
A smear from a 65 yr old postmenopausal woman contains many eosinophilic parabasal like cells with
small pyknotic nuclei. The most likely diagnosis is: - ANSWER-Atrophic vaginitis
