Unbound fraction - Guides d'étude, Notes de cours & Résumés

PCOL 355 E2 Exam Questions with Correct A An inert gas is needed for density measurements. a. True b. False - Answer-true The Compressibility Index and Hausner ratio of a pharmaceutical powder are identical. a. True b. False - Answer-false The bulk density and tapped density of a pharmaceutical powder are identical. a. True b. False - Answer-false The surface area and specific surface area of a pharmaceutical powder are identical. a. True b. False - Answer-false What is the key ...

Describe the general structures of norepinephrine & epinephrine - Answer - aromatic ring with 2 hydroxyl groups - secondary hydroxyl group - amine group NE & EPI are susceptible to rapid metabolism/elimination by the enzymes ___ & ___ , resulting in extremely short half-lives - Answer COMT & MAO Predict the effects of N-alkyl group size on beta-AR activity - Answer inc bulkiness of N-alkyl group = inc binding affinity for beta-2 AR (more selective for beta-2 & binds longer) Which stru...

Katzung & Trevor's Pharmacology: Examination and Board Review INTRODUCTION 1. A 3-year-old is brought to the emergency department having just ingested a large overdose of tolbutamide, an oral antidiabetic drug. Tolbutamide is a weak acid with a pKa of 5.3. It is capable of entering most tissues, including the brain. On physical examination, the heart rate is 100/min, blood pressure 90/50 mm Hg, and respiratory rate 20/min. Which of the following statements about this case of tolb...

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PHARM_STUDY_GUIDE_QUIZ_ 1.2023 1. What are the BON rules and regulations for prescriptive authority for the advance practice nurse? 1. Texas is very restricted 2. Describe the pharmacokinetic processes of absorption, distribution, metabolism and elimination and how differences in these areas affect drug action. 1. Absorption 1. Drug’s movement from the site of administration into the blood. 2. Distribution 1.Drug’s movement from the blood into the interstitial space oftissues and ...

Drug - ANSWER-any chemical that can affect living processes. Pharmacology - ANSWER-the study of drugs and their interactions with living systems. or the total knowledge of drugs including history, chemistry, source, biochemical & physical effects Clinical Pharmacology - ANSWER-the study of drugs in humans, this discipline includes the study of drugs in patient's and healthy volunteers (during drug development) Therapeutics - ANSWER-AKA: pharmacotherapeutics; is defined as the use of dr...

PHARM_STUDY_GUIDE_QUIZ_ 1.2023 1. What are the BON rules and regulations for prescriptive authority for the advance practice nurse? 1. Texas is very restricted 2. Describe the pharmacokinetic processes of absorption, distribution, metabolism and elimination and how differences in these areas affect drug action. 1. Absorption 1. Drug’s movement from the site of administration into the blood. 2. Distribution 1.Drug’s movement from the blood into the interstitial space oftissues and ...

Chapter 28 Additional patient variables: Angina and Concomitant Diseases and drugs to treat them Angina and Myocardial Infarction aspirin and beta blockers *ACE inhibitors are the drug of choice to treat angina in patients with diabetes or left ventricular dysfunction. Angina and Heart Failure ACE inhibitors are first line patients who cannot tolerate ACE inhibitors are being prescribed ARBs Hypertension and Angina lifestyle modifications are the first approach to treatment for pa...

1. Discuss the 4 Principles of Practice - answer-a. Safety is paramount b. Adhere to ethical practices c. Value base system health care delivery d. Prevention and early migration of disease 1. Identify the appropriate age and interval of recommended health screening for women. - answer-a. Woman 19-49 MMR, hep b, and varicella for those non immune. b. Girls 11-26 HPV vaccine c. Tdap 19-64 replace Td d. Women 50> influenza annually i. 19-49 annually for health care workers ii. Chroni...

For a drug to produce an effect it must overcome an individual's - ANSWER Homeostasis: physio processes meant to maintain internal cell environment What is a graded drug response? Examples? - ANSWER Biological effects that can be measured (blood pressure, HR, diuresis, pain, coma, brochodilation) What is a quantal drug response? Examples? - ANSWER Effects that may or may not occur, not necessarily measured (pregnancy, seizures, rash, sleep, death) _______ is the expression of how much ...