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ATI PHARMACOLOGY PROCTORED EXAM | 95 NGN QUESTIONS WITH 100% CORRECT ANSWERS| RATED A+| VERSION 1
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ATI PHARMACOLOGY PROCTORED EXAM | 95 NGN QUESTIONS WITH 100% CORRECT ANSWERS| RATED A+| VERSION 1
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ATI PHARMACOLOGY PROCTORED EXAM 2024-2024| 95 NGNQUESTIONS WITH 100% CORRECT ANSWERS| RATED A+| VERSION 1
A practicing nurse is preparing to administer Cyclophosphamide IV to a client who has
Hodgkin's disease. Which of the following medications should the practicing nurse expect
to administer concurrently with the chemotherapy to prevent an adverse effect of
Cyclophosphamide?
A. Uroprotectant agent, such as mesna
B. Opioid, such as morphine
C. Loop diuretic, such as furosemide
D. H1 receptor antagonist, such as diphenhydramine - RIGHT CHOICE<><> A
(Mesna is a uroprotectant agent that can help prevent hemorrhagic cystitis when
administered IV with a nitrogen mustard chemotherapy medication)
A practicing nurse is preparing to administer Leucovorin to a client who has cancer and
is receiving chemotherapy with Methotrexate. Which of the following responses should
the practicing nurse use when the client asks why Leucovorin is being given?
A. "Leucovorin reduces the risk of a transfusion reaction from methotrexate."
B. "Leucovorin increases platelet production and prevents bleeding."
C. "Leucovorin potentiates the cytotoxic effects of methotrexate."
D. "Leucovorin protects healthy cells from methotrexate's toxic effect." - RIGHT
CHOICE<><> D (Leucovorin, a folic acid derivative and an antagonist to methotrexate,
is given within 12 hr of high doses of methotrexate to protect healthy cells from the
toxic effects of methotrexate)
A practicing nurse is teaching a client who has breast cancer about Tamoxifen. Which of
the following adverse effects of tamoxifen should the practicing nurse discuss with the
client?
A. Irregular heart beat
B. Abnormal uterine bleeding
C. Yellow sclera or dark-colored urine.
D. Difficulty swallowing - RIGHT CHOICE<><> B (Vaginal discharge and bleeding are
adverse effects of tamoxifen. The client who takes tamoxifen is also at increased risk for
endometrial cancer, so any abnormal uterine bleeding should be carefully monitored
and evaluated)
A practicing nurse is caring for a client who is being treated with Interferon alfa-2b for
Malignant Melanoma. For which of the following adverse effects should the practicing
nurse monitor? (Select all that apply.)
A. Tinnitus
B. Muscle aches
C. Peripheral neuropathy
1|P ag e
,D. Bone loss
E. Depression - RIGHT CHOICE<><> b, c, e
(B.muscle aches and other flu-like manifestations are common adverse effects of
interferon alfa-2b. Acetaminophen may be prescribed to relieve these manifestations.
C. Peripheral neuropathy, dizziness, and fatigue are CNS effects that can occur when
taking interferon alfa-2b. These should be reported to the provider, and the practicing
nurse should teach the client to prevent injury from falls.
E. Depression and mental status changes
can occur with interferon alfa-2b treatment. The practicing nurse should assess the
client for suicidal thoughts.)
A practicing nurse is caring for a client who receives Rituximab to treat Non-hodgkin's
Leukemia and who asks the practicing nurse how Rituximab works. Which of the
following should the practicing nurse include?
A. Blocks hormone receptors
B. Increases immune response
C. Binds with specific antigens on tumor cells
D. Stops DNA replication during cell division - RIGHT CHOICE<><> C (Rituximab is a
monoclonal antibody that binds to specific antigens on B-lymphocytes and then
destroying cancer cells.)
A practicing nurse is implementing a plan of care for a client who has a wound infection.
Which of the following actions should the practicing nurse perform first?
A. Administer antibiotic medication.
B. Obtain a wound specimen for culture.
C. Review WBC laboratory findings.
D. Apply a dressing to the wound - RIGHT CHOICE<><> B (When using the urgent
vs. nonurgent approach to care, the nurse's priority action is to obtain a culture of the
wound before initiating antibiotic therapy)
A practicing nurse is caring for a client who has a UTI and a history of recurrence of this
type of infection. The client asks why the provider has not yet prescribed an antibiotic.
The practicing nurse should explain that the provider has to wait for the results of which
of the following laboratory tests to identify which antibiotic to prescribe?
A. Gram stain
B. Culture
C. Sensitivity
D. Specific gravity - RIGHT CHOICE<><> C (A sensitivity test identifies the most effective
antibiotic to prescribe to treat a specific micro-organism.)
2|P ag e
, A practicing nurse is preparing information for the unit's nurses about the effectiveness
of antimicrobial therapy for clients who have bacterial infections. Which of the following
host factors should the practicing nurse include as conditions that affect antimicrobial
effectiveness? (Select all that apply.)
A. Meningitis
B. Pacemaker
C. Endocarditis
D. Pneumonia
E. Pyelonephriti - RIGHT CHOICE<><> a, b, c
(A. Some clients who have meningitis have
difficulty responding to antimicrobial therapy because it is difficult for the medication to
cross the blood-brain barrier to reaching the infecting micro-organisms.
B. Some clients who have a pacemaker have difficulty responding to antimicrobial
therapy due to colonization of micro-organisms around the pacemaker and the inability
of phagocytic cells to destroy those micro-organisms.
C. Some clients who have endocarditis have
difficulty responding to antimicrobial therapy because the medication cannot penetrate
the vegetative thrombus that develops on the injured endocardium)
A practicing nurse is caring for a group of clients who are receiving antimicrobial therapy.
Which of the following clients should the practicing nurse plan to monitor for
manifestations of antibiotic toxicity?
A. An adolescent client who has a sinus infection
B. An older adult client who has prostatitis
C. A client who is postpartum and has mastitis
D. A middle adult client who has a urinary tract infection - RIGHT CHOICE<><> B (An
older adult client who has prostatitis and is receiving antibiotics is at risk for toxicity due
to the age-related reduction in medication metabolism and excretion)
A charge practicing nurse is teaching a group of nurses about the importance of
prophylactic antimicrobial therapy. Which of the following information should the charge
practicing nurse include in the teaching? (Select all that apply.)
A. Administer prophylactic antimicrobial therapy to clients who report exposure to a
sexually transmitted infection.
B. Administer prophylactic antimicrobial therapy to clients who are having orthopedic
surgery.
C. Instruct clients who have a prosthetic heart valve about the need for prophylactic
antimicrobial therapy before dental work.
3|P ag e
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