NBME Biochemistry Shelf Exam Questions and Complete Verified Solutions 2024

NBME Biochemistry Shelf Exam Questions and Complete Verified Solutions 2024 What neurotransmitter stimulates release of epinephrine from adrenal medulla? acetylcholine What is a metabolite if epinephrine that suggests epi -secreting carcinoma? What is another assoc symptom? metanephrine; assoc with HBP What does acetazolamide (carbonic anhydrase ib) treat? glaucoma, epilepsy, altitude sickness, congestive heart failure can cause dehydration Sickle cell anemia is due to... pt mutation of Glu -> val What is a major neurotransmitter amino acid? Glu HA protein of influenza binds to cytokine receptors What is a reducing -sugar test? Tests for aldo -keto sugars What is omeprazole? proton pump ib Name some GAG's. heparin sulfate, chondroitin sulfate, What type of reaction is glucuronidation? oxidation In Marfan's syndrome, what part of fibrillin's protein structure is affected? primary structure What are the symptoms of Huntington's disease? anxiety, uncontrollable mvmts, slurring of speech, difficulty focusing or concentrating; caused by triple repeat expansion What is Chediak -Higashi syndrome? phagocyte deficiency -> hypergammaglobulinemia, significant neutropenia, In exposure to carbon monoxide or cyanide, which way does the ox sat curve shift? to the L; increased affinity at low pO_2 What is pralidoxime chloride? reactivate acetylcholinesterase Wernicke encephalopathy inadequate thiamine; confusion, ophthalmoplagia (nystagmus) What is the function of lactase? beta(1 ->4) galactosidase; cleaves Gal fro m Glu How is fructose absorbed? via sodium -independent transporter What sugar enzymes are found on the intestinal brush border? sucrase, lactase, maltase, isomaltase Orlistat ib pancreatic and gastric lipase; leads to reduced fat digestion