SBB Study Guide Questions with Correct Answers A Grade (1)

SBB Study Guide Questions with Correct Answers A Grade (1) What enzyme may be useful in distinguishing anti-Ge2 from anti-Ge3? - Answer-Papain (Anti-Ge2 will not react) The beta 1-3 linkage between galactose and N-actylglucosamine is found in: - Answer- Secretions Which of the following represents the Type II chain? - Answer-Beta 1-4 linkage between galactose and N acetyl glucosamine Rank the order of decreasing H concentration on RBCs - Answer- 0>A2>B>A2B>A1>A1B All of the following are genotypes for the A1 phenotype except: 1. A1/A1 2. A1/A2 3. A2/B 4. A1/O - Answer-A2/B The ABO genes are located on which chromosome? - Answer-9 Which glycosyltransferase is needed before A and B antigens are formed? - Answer-L- fucosyltransferase What is the typical reaction of the A3 subgroup? - Answer-mixed field reaction with Anti- A and Anti-A,B What is the typical reaction of the Ael subgroup? - Answer-Positive reaction with anti-H What clinical condition may yield positive reactions with Anti-A, negative with Anti-B, negative with A1 and B cells. - Answer-Hypogammaglobulinemia What differentiates a Bombay anti-H from an anti-H cold agglutin? - Answer-Reactivity at body temperature The is antigen is associated with linear carbohydrate chains? - Answer-i antigen The following reactions are found on a 35 yr old male. Anti-A 4+, Anti-B 0, Anti-A,B-4+, A1 cells 3+, B cells 4+, O cells 3+. How could these be explained? - Answer-Anti-M in plasma Anti-IH would react best with which RBC? - Answer-O The acquired B phenomenon is only found in which ABO group? - Answer-A Which of the following is true about the A2 subgroup? 1. 1-8% of persons will product anti-A1 2. Anti-A1 does not react with A2 RBCs 3. Anti-A2 is formed 4. Two of the above - Answer-Two of the above (1-8% of persons will product anti-A1 and Anti-A1 does not react with A2 RBC ) Anti-Lu3 is associated with: - Answer-Recessive type Lu(a-b-) The dominant Lu(a-b-) type is associated with what gene? - Answer-In(Lu) What substance could be used to rule out anti-E in the presence of anti-Lub? - Answer- DTT Which pair of alleles is out of place? 1. Lu8/Lu14 2. Lu8/Lu10 3. Lu6/Lu9 4. Aua/Aub - Answer-Lu8/Lu10 Persons who are group B are more common among which population? - Answer- Black/Asian Red cells that lack glycophrin A also lack: - Answer-Ena antigens Anti-ENKT reacts with which RBCs? - Answer-ENaFS What is a lectin? - Answer-Seed extracts that agglutinate human cells with moderate specificity All of the following are representative of Lewis antibodies, except? 1. They can be neutralized by Lewis substance 2. They occur frequently in pregnant women 3. They are destroyed by enzymes 4. They are enhanced by enzymes - Answer-They are destroyed by enzymes