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TEST BANK Cellular and Molecular Immunology 10th Edition Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, 9780323757485 (CHAPTERS 1-21)
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TEST BANK Cellular and Molecular Immunology 10th Edition Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, 9780323757485 (CHAPTERS 1-21)
Cellular and Molecular Immunology Tenth Edition Test Bank / Cellular and Molecular Immunology, 10th Edition Test Bank / Test Bank Cellular and Molecular Immunology...
TEST BANK
Test Bank for Cellular and Molecular Immunology
10th Edition by Abul K. Abbas, Andrew Lichtman, Shiv Pillai
CELLULAR AND MOLECULAR IMMUNOLOGY
TENTH EDITION
ABBAS, LICHTMAN, PILLAI
, Table of Contents:-
Chapter1 Properties and Overview of Immune Responses
Chapter2 Cells and Tissues of the Immune System
Chapter3 Leukocyte Circulation and Migration into Tissues
Chapter4 Innate Immunity
Chapter5 Antibodies and Antigens
Chapter6 Antigen Presentation to T Lymphocytes and the Functions of
MHC Molecules
Chapter7 Immune Receptors and Signal Transduction
Chapter8 Lymphocyte Development and Antigen Receptor Gene
Rearrangement
Chapter9 Activation of T Lymphocytes
Chapter 10 Differentiation and Functions of CD4+ Effector T Cells
Chapter 11 Differentiation and Functions of CD8+ Effector T Cells
Chapter 12 B Cell Activation and Antibody Production
Chapter 13 Effector Mechanisms of Humoral Immunity
Chapter 14 Specialized Immunity at Epithelial Barriers and in Immune
Privileged Tissues
Chapter 15 Immunologic Tolerance and Autoimmunity
Chapter 16 Immunity to Microbes
Chapter 17 Transplantation Immunology
Chapter 18 Immunity to Tumors
Chapter 19 Hypersensitivity Disorders
Chapter 20 Allergy
Chapter 21 Congenital and Acquired Immunodeficiencies
,Abbas, Lichtman, and Pillai: Cellular and Molecular Immunology, 10th
Edition
Test Bank
Chapter 1: Properties and Overview of Immune Responses
Multiple Choice
The principal function of the immune system is:
A. Defense against cancer
B. Repair of injured tissues
C. Defense against microbial infections
D. Prevention of inflammatory diseases
E. Protection against environmental toxins
ANS: C. The immune system has evolved in the setting of selective pressures imposed by
microbial infections. Although immune responses to cancer may occur, the concept that
“immunosurveillance” against cancer is a principal function of the immune system is
controversial. Repair of injured tissues may be a secondary consequence of the immune
responses and inflammation. Although the immune system has regulatory features that are
needed to prevent excessive inflammation, prevention of inflammatory diseases is not a primary
function. The immune system can protect against microbial toxins, but it generally does not offer
protection against toxins of nonbiologic origin.
2. Which of the following infectious diseases was prevented by the first successful
vaccination?
A. Polio
B. Tuberculosis
C. Smallpox
D. Tetanus
E. Rubella
ANS: C. In 1798, Edward Jenner reported the first intentional successful vaccination, which was
against smallpox in a boy, using material from the cowpox pustules of a milkmaid. In 1980,
smallpox was reported to be eradicated worldwide by a vaccination program. Effective vaccines
against tetanus toxin, rubella virus, and poliovirus were developed in the 20th century and are
widely used. There is no effective vaccine against Mycobacterium tuberculosis.
3. Which of the following is a unique property of the adaptive immune system?
A. Highly diverse repertoire of specificities for antigens
B. Self-nonself discrimination
C. Recognition of microbial structures by both cell-associated and soluble receptors
D. Protection against viral infections
E. Responses that have the same kinetics and magnitude on repeated exposure to the same
microbe
, ANS: A. Highly diverse repertoires of specificities for antigens are found only in T and B
lymphocytes, which are the central cellular components of the adaptive immune system. Both the
innate and the adaptive immune systems use cell-associated and soluble receptors to recognize
microbes, display some degree of self-nonself discrimination, and protect against viruses. On
repeated exposure to the same microbe, the adaptive immune response becomes more rapid and
of greater magnitude; this is the manifestation of memory.
4. Antibodies and T lymphocytes are the respective mediators of which two types of
immunity?
A. Innate and adaptive
B. Passive and active
C. Specific and nonspecific
D. Humoral and cell-mediated
E. Adult and neonatal
ANS: D. Both B and T lymphocytes are principal components of adaptive immunity. B
lymphocytes produce antibodies, which are the recognition and effector molecules of humoral
immune responses to extracellular pathogens. T cells recognize and promote eradication of
intracellular pathogens in cell-mediated immunity. Passive and active immunity both can be
mediated by either B or T lymphocytes. Specific immunity is another term for adaptive immunity.
Both B and T lymphocytes participate in adult adaptive immunity but are still developing in the
neonatal period.
5. The two major functional classes of effector T lymphocytes are:
A. Helper T lymphocytes and cytotoxic T lymphocytes
B. Natural killer cells and cytotoxic T lymphocytes
C. Memory T cells and effector T cells
D. Helper cells and antigen-presenting cells
E. Cytotoxic T lymphocytes and target cells
ANS: A. T cells can be classified into effector subsets that perform different effector functions.
Most effector T cells are either helper T lymphocytes, which enhance the responses of other
immune cells, including phagocytes and B cells, to infections, or cytotoxic T lymphocytes, which
directly kill infected cells. Natural killer cells are not T lymphocytes. Antigen-presenting cells
usually are not T cells. Memory T cells are not effector T cells.
6. Which of the following cell types is required for all adaptive humoral immune responses?
A. Natural killer cells
B. Dendritic cells
C. Cytolytic T lymphocytes
D. B lymphocytes
E. Helper T lymphocytes
ANS: D. Humoral immune responses are antibody-mediated immune responses, and all
antibodies are made by B lymphocytes and no other cell type.
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