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CWS exam Practice Questions and Answers 100% Pass Cells make up the Epidermis? - ANSWER-Keratinocytes Keratinocytes are? - ANSWER-in stratum granulosum, relase lipids which continaun moisture, brick and mortar of skin Dermis contains? - ANSWER-cells for i €13,26   In winkelwagen

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CWS exam Practice Questions and Answers 100% Pass Cells make up the Epidermis? - ANSWER-Keratinocytes Keratinocytes are? - ANSWER-in stratum granulosum, relase lipids which continaun moisture, brick and mortar of skin Dermis contains? - ANSWER-cells for i

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CWS Exam Prep Questions and Answers 100% Pass Name the five types of Cell Adhesion Molecules? Which type enables cells to detect and interact with components of the extracellular matrix? - ANSWER-1. Cadherins 2. Immunoglobulin Superfamily (IGSF) 3. Selectins 4. Integrins 5. Mucins Integrins...

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CWS Exam Prep Questions and Answers

100% Pass


Name the five types of Cell Adhesion Molecules? Which type enables cells to detect and interact with

components of the extracellular matrix? - ANSWER✔✔-1. Cadherins


2. Immunoglobulin Superfamily (IGSF)


3. Selectins


4. Integrins


5. Mucins




Integrins allow cells to interact with the surrounding environment or components of the ECM.


What are the layers of the epidermis from most superficial to most deep? - ANSWER✔✔-Stratum

corneum


Stratum lucidum


Stratum granulosum


Stratum spinosum


Stratum basale (germinativa)


What are the layers of the dermis from most superficial to most deep? - ANSWER✔✔-Papillary dermis



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Reticular dermis


What is/are the primary cell type(s) of the stratum spinosum? - ANSWER✔✔-Langerhan's cells


What is/are the primary cell type(s) of the stratum basale? - ANSWER✔✔-Keratinocytes, Melanocytes,

Merkel cells


What is/are the primary cell type(s) of the stratum granulosum? - ANSWER✔✔-Corneocytes (terminally

differentiated keratinocytes)


What is/are the primary cell type(s) of the stratum corneum? - ANSWER✔✔-Dead keratinocytes


What is/are the primary cell type(s) of the dermis? - ANSWER✔✔-Fibroblasts, Mast cells, Macrophages,

Lymphocytes


Tissue loss includes only the epidermis. - ANSWER✔✔-Superficial


Tissue loss includes the epidermis and part of the dermis. - ANSWER✔✔-Partial thickness


Tissue loss includes the epidermis and all of the dermis. - ANSWER✔✔-Full thickness


Tissue loss includes subcutaneous tissues. - ANSWER✔✔-Subdermal


When does hemostasis or coagulation occur during the stages of healing? - ANSWER✔✔-Immediately

after tissue injury


When does inflammation occur during the stages of healing? - ANSWER✔✔-0-4 days


When does proliferation occur during the stages of healing? - ANSWER✔✔-4-21 days


How long can remodeling last? - ANSWER✔✔-Up to 2 years


What are the key cells of hemostasis? - ANSWER✔✔-Platelets

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What are the key cells of inflammation? - ANSWER✔✔-Neutrophils, Macrophages


What are the key cells of proliferation? - ANSWER✔✔-Fibroblasts, Epithelial cells, Endothelial cells,

Macrophages


What are the key cells of remodeling? - ANSWER✔✔-Fibroblasts


What produces PDGF? - ANSWER✔✔-Platelets and macrophages


What stimulates fibroblasts? - ANSWER✔✔-Platelet Derived Growth Factor


What is an integrin? - ANSWER✔✔-A cell surface receptor that enables cells to interact with components

of the ECM


What secretes MMPs and TIMPs? - ANSWER✔✔-Keratinocytes and fibroblasts


What regulates the activity of MMPs? - ANSWER✔✔-TIMPs


Fibroblasts play a key role in the extracellular matrix deposition of which types of proteins? -

ANSWER✔✔-Collagen


Elastin


Reticulin


Proteoglycans


Glycosaminoglycans


Myofibroblasts secrete which type of collagen? - ANSWER✔✔-Type I


Which type of collagen is primarily found in uninjured tissue? - ANSWER✔✔-Type I




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Which type of collagen is primarily found in wounds in the proliferative phase of wound healing? -

ANSWER✔✔-Type III


What is the transitional marker between the inflammatory and proliferative phases of healing? -

ANSWER✔✔-Macrophage migration into the wound site


Which cells are the last to arrive during the proliferative phase? - ANSWER✔✔-T lymphocytes


What are the three types of T lymphocytes and what are their functions? - ANSWER✔✔-1. Cytotoxic T

cells = directly target and kill any antigen-bearing cells


2. Helper T cells = activate macrophages and B lymphocytes


3. Suppressor T cells = down regulate inflammation and proliferation as the wound reaches maturity


What is considered the "first line of defense" in wound healing? - ANSWER✔✔-Neutrophils (PMN

leukocytes)


Mast cells are characterized by extensive cytoplasm with large granules which contain: - ANSWER✔✔-1.

Histamine


2. Heparin


3. Eicosanoids


4. Serotonin


5. Chondroitin sulfate


6. Vasoactive proteins


What type of collagen is primarily found in skin, tendon, vascular ligature, organs and bone (most

common in wounds)? - ANSWER✔✔-Type I

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