University College London (UCL) • Biology

Process and uses of molecular and protein techniques

Mitochondria structure, function, experiments used to elucidate function, mitochondrial disease

First 2 introduction lectures to the course - what is an organelle, definition of an organelle, information on the nucleus, endoplasmic reticulum, chloroplast, peroxisomes, lysosomes, some non-organelles and a brief note on the evolutionary origin of organelles

Neural Crest specification, regionalisation - summary of the whole lecture from BIOL2010 module.

Covers 2 lectures on organelle structure and function, as well as biogenesis (eg. localisation signals, detailed pathways of directing nutrients and components for biogenesis - to the nucleus, mitochondria, peroxisomes etc.) Extra reading with sources cited.

Sea urchin regulatory programme - negative feedback loops, autonomous specification of PMCs and experimental data that support the findings - extra reading with sources cited

Sea Urchin Embryogenesis - from cleavage to tissue differentiation, covering the generation of PMCs in extensive detail (Extra reading with sources cited)

Theories of ageing with a connection to development - part of the BIOL2010 lectures with extra reading

Xenopus specification of cell fates - genetic and cellular mechanisms from the lecture with extra reading

Xenopus mesoderm formation and the various genetic signals - whole lecture covered with extra reading from textbooks and papers