NUR 312

4 Phenotypes of Metabolizers ● UM: Ultrarapid responders ○ Active drugs: ineffective ○ Prodrug: toxic ● EM: Extensive Responders ○ Active drug & prodrug: possibly therapeutic ● IM: Intermediate Responders ○ Active drug & prodrug: possibly therapeutic ● PM: Poor Responders ○ Active drug: toxic ○ Prodrug: ineffective

● Respiratory and GI Meds : Approximately 20 questions: ● Albuterol:mechanism of action, therapeutic effects, side effects ○ Most effective class of drugs for relief of acute bronchospasm and prevention of exercise-induced bronchospasm ○ Used in asthma: both quick relief and long term control ○ Generally inhaled, but oral route is also available ○ Produce bronchodilation with relief of bronchospasm and bronchoconstriction ○ Suppress histamine release and increase ciliary mot...

ncreases metabolic rate, protein synthesis, cardiac output, renal perfusion, oxygen use, body temperature, blood volume and growth processes ● Treatment of hypothyroidism ● Contraindications: ○ Use is contraindicated for patients with have thyrotoxicosis and adrenal insufficiency ○ Contraindication following a MI ○ Use cautiously in older adults and pt with diabetes ○ Preg. category 1 ● Dosing: ○ Begins with a low dose in the mornings that gradually increases over 6-8 ...