NUR 0302 481
Adelphi University
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Physiological Changes with Aging at a Glance.
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TABLE 14-1 Common Physiological Changes with Aging at a Glance 
Fundamentals of Nursing, 8th Edition 
SYSTEM COMMON CHANGES 
Integumentary 
Loss of skin elasticity with fat loss in extremities, pigmentation changes, glandular 
atrophy (oil, moisture, sweat glands), thinning hair, with hair turning gray-white (facial 
hair: decreased in men, increased in women), slower nail growth, atrophy of epidermal 
arterioles 
Respiratory 
Decreased cough reflex; decreased cilia; increased anterior-posterior...
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Adelphi UniversityNUR 0302-481disgnostic studies.
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Colonoscopy 
• An endoscopic examination of the entire colon uses a 
colonoscope inserted into the rectum. 
• Preparation is similar to that for barium enema: clear liquids 
the day before and then some form of bowel cleanser such as 
GoLytely. Enemas until clear are also common. 
• Light sedation is required 
Flexible Sigmoidoscopy 
• An examination of the interior of the sigmoid colon with 
a flexible or rigid lighted tube. 
• Preparation is similar to that for a barium enema or 
col...
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Adelphi UniversityNUR 0302-481Medsurg Drugs.
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Cyclophosphamide (Cytoxan): 
 SE: Hemorrhagic cystitis 
 Give Mensa beforehand to protect bladder 
 SE: SIADH – watch for hyponatremia 
Cisplatin (platinolOxaliplatin): 
 Nephrotoxic & ototoxic (to whisper test) 
 Cold sensitivity (wears jacket when its warm out) 
Doxorubicin (Adriamycin) RED DEVIL 
 SE: Severe Cardio Toxicity. 
 Echo & ejection fraction needs to be WNL 
 Know S/S of Heart Failure. 
 SE: Severe Bone marrow suppression, mucositis. 
 Very toxic (c...
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Arthritis & Other Connective Tissue Diseases
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Rheumatology 
 Connective tissue disease (CTD) major focus 
 Non-inflammatory or inflammatory 
 Rheumatic disease = any disease/ condition involving 
musculoskeletal system 
 Arthritis = inflammation of one or more joints 
 Non-inflammatory localized arthritis (osteoarthritis) is 
not systemic, not an autoimmune disease 
 Inflammatory arthritis: 
o Rheumatoid arthritis 
o Systemic lupus erythematosus 
o Autoimmune disease 
Joint Changes in Degenerative Joint Disease 
Osteoarthr...
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