NURSING NURS 5315 (NURS5315)
University Of Texas - Arlington
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N5315 Advanced PathophysiologyGastrointestinalCore Knowledge Objectives with Advanced Organiz/GI system- Module 9
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N5315 Advanced Pathophysiology 
Gastrointestinal 
Core Knowledge Objectives with Advanced Organizers 
Gastrointestinal Bleeds 
1. Analyze the etiology, clinical manifestations, and pathophysiology of the upper and lower GI 
bleed and describe the implications this has for your clinical practice as a nurse practitioner. 
Disease Etiology Clinical 
Manifestations 
Pathophysiology Implications for 
Practice 
Upper 
GI 
Bleed 
Bleeding varices 
(varicose veins) in 
the esophagus or 
stomach, peptic ...
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N5315 Advanced Pathophysiology Hematologic System Prerequisite Knowledge Objectives with Advanced Organizers
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N5315 Advanced Pathophysiology 
Hematologic System 
Prerequisite Knowledge Objectives with Advanced 
Organizers 
Hematologic Anatomy and Physiology 
1. Analyze the normal structure and function of the following
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N5315 Advanced Pathophysiology Hematologic System Prerequisite Knowledge Objectives with Advanced Organizers
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Hematologic Anatomy and Physiology 
1. Analyze the normal structure and function of the following cells/organs. CH 27 
Cell/Organ Structure and Function 
Erythrocytes & 
Iron Cycle 
FIGURE 27-17 
(RBC’s) most abundant cell of the body. Responsible for tissue 
oxygenation. Contains: Hemoglobin, Electrolytes, [A mature 
erythrocyte=no nucleus/no mitochondria, cannot synthesize protein/carry 
out oxidative reactions]. Short life d//t no mitosis=100-120 days. 
Biconcave disk/can be reversibly defo...
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N5315 Advanced Pathophysiology Gastrointestinal Core Knowledge Objectives with Advanced Organizers Gastrointestinal Bleeds
- Exam (elaborations) • 25 pages • 2023
- Available in package deal
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- $9.49
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N5315 Advanced Pathophysiology 
Gastrointestinal 
Core Knowledge Objectives with Advanced Organizers 
Gastrointestinal Bleeds 
1. Analyze the etiology, clinical manifestations, and pathophysiology of the upper and lower GI 
bleed and describe the implications this has for your clinical practice as a nurse practitioner. 
Disease Etiology Clinical 
Manifestations 
Pathophysiology Implications for 
Practice 
Upper 
GI 
Bleed 
Bleeding varices 
(varicose veins) in 
the esophagus or 
stomach, peptic ...
-
N5315 Advanced PathophysiologyGeneticsCore Knowledge Objectives with Advanced Organizers
- Exam (elaborations) • 7 pages • 2023
- Available in package deal
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N5315 Advanced Pathophysiology 
Genetics 
Core Knowledge Objectives with Advanced Organizers 
Genetics 
Chapter 4 
1. Analyze the pathological processes which alter the structure and role of the DNA and 
RNA molecules. 
a. Describe the structure and function of the DNA molecule and its clinical 
significance. PAGE 136-137 
i. Four types of nitrogenous bases of DNA include adenine, cytosine, 
guanine, and thymine commonly represented as their first letter. Physical 
structure of DNA is the double...
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NURS 5315 Disorders of the Immune System
- Exam (elaborations) • 6 pages • 2023
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Disorders of the Immune System 
2. Differentiate between the etiology, clinical manifestations and pathophysiology of 
select disorders of the immune system. 
Hypersensitivity: an altered immunologic response to an antigen that results in disease 
or damage to the host. 
Hypersensitivity reaction: can be classified in 2 ways 
- by the source of the antigen that the immune system is attacking (allergy, 
autoimmunity, alloimmunity) 
- by the mechanism that causes the disease (types I, II, III, IV)...
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N5315 Advanced Pathophysiology Inflammation and Altered Immunity Core Knowledge Objectives with Advanced Organizers
- Exam (elaborations) • 17 pages • 2023
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N5315 Advanced Pathophysiology 
Inflammation and Altered Immunity 
Core Knowledge Objectives with Advanced Organizers 
Inflammation 
1. Examine the process of inflammation. 
a. Analyze the role and function of the key players in the inflammatory process and describe 
the implications for clinical practice. 
Key Player Role and Function 
Mast Cell - Central cells of inflammation and release histamine, chemotactic factors, 
cytokines, leukotrienes, prostaglandins, growth factors, and other mediato...
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N5315 Advanced Pathophysiology Hematologic System Core Knowledge Objectives with Advanced Organizers
- Exam (elaborations) • 7 pages • 2023
- Available in package deal
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N5315 Advanced Pathophysiology 
Hematologic System 
Core Knowledge Objectives with Advanced Organizers 
Disorders of Hemostasis 
1. Examine the etiology, clinical manifestations, and the pathophysiology of disorders of 
hemostasis. 
a. Discuss how the
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N5315 Advanced Pathophysiology Endocrine Prerequisite Knowledge Study Objectives
- Exam (elaborations) • 7 pages • 2023
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N5315 Advanced Pathophysiology 
Endocrine 
Prerequisite Knowledge Study Objectives 
Hormones of the Hypothalamus and Pituitary Gland 
1. Analyze the role of hormones produced by the hypothalamus and pituitary gland. 
a. Create scripts for explaining the following to a patient or colleague in layman’s 
terms which explain the glands of the endocrine system, the hormones they 
produce, the target tissue and the hormone function to patients or colleag
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