Carmustine bcnu Study guides, Class notes & Summaries
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Chemotherapy Questions With Complete Solutions
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What do alkylating agents do? correct answer: Active throughout cell cycle. Causes breaks in DNA helix, preventing replication and transcription of RNA. 
 
What are the alkylating agent drugs? correct answer: Bendamustine (Treanda) 
Busulfan (Myleron) 
Carboplatin (Paraplatin) 
Carmustine (BCNU) 
Chlorambucil (Leukeran) 
Cisplatin (Platinol, CDDP) 
Cyclophosphamide (Cytoxan, CTX) 
Dacarbazine (DTIC) 
Ifosfamide (Iflex) 
Mechlorethamine (Nitrogen Mustard) 
Melphalan (Alkeran) 
Oxaliplatin (Elo...
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BMTCN Review Chapter 4 - Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and Engraftment 2023/2024
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BMTCN Review Chapter 4 - Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and EngraftmentTRANSPLANT PREP REGIMENS - correct answer Treatment leading up to transplant 
 
Acronyms: 
Ara-C 
BCNU 
BU 
Cy 
DLT 
SCT 
TBI - correct answer Cytarabine 
Carmustine 
Busulfan 
Cyclophosphamide 
Dose limiting toxicity 
DStem cell transplant 
Total body irradiation 
 
Induction chemotherapy - correct answer The first treatment given for a disease. It is often part of a standard set of ...
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BMTCN questions with verified solutions graded A+ 2023/2024
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BMTCN 
ATG - correct answer anti t-cell globulin 
prevents GVHD, graft failure 
premeds: Tylenol, corticosteroids, Benadryl 
SE: hypotension, chills, rigors, fevers, pulmonary edema 
 
serum sickness - correct answer ATG 
myalgias, arthralgias, fever, rash, hand/facial edema 
give steroids 
 
BCNU (carmustine) - correct answer alkylating agent 
pre/post hydration 
SE: n/v, nephrotoxicity (elevated creat), pulmonary toxicity (pulmonary fibrosis, acute lung injury) 
infusion rx: feeling drunk, hy...
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BMTCN Chapter 4 questions with 100% correct answers rated A+
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BMTCN Chapter 4 
BCNU - correct answer Carmustine 
Causes DNA Cross links and strand breaks 
Inhibits DNA repair 
Crosses blood/brain barrier 
Need pre/post hydration 
 
BCNU Side Effects - correct answer N/V 
Infusion reactions 
nephrotoxicity (increased Crea & BUN) 
pulmonary - cough, dyspnea, tachypnea 
acute lung injury - 10-30 days post infusion (tx w/ steroids; can be fatal) 
 
Busulfan - correct answer *Alkylating agent*-->cross-links DNA-->damages DNA 
 
Crosses blood brain barrier...
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BMTCN Medication Question and answers correctly solved 2023/2024
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BMTCN Medication Question and answers correctly solved 2023/2024 
ATG - correct answer Immune Suppressant. 
not recommended for reduced intensity regimens 
s/s pulm edema, hepatic dysfunction. 
Skin rash,joint pains(serum Sickness-TREATED WITH STEROIDS) 
Used before Allo for immunosuppression and later to treat GVHD. 
 
BCNU(carmustine) - correct answer nephro toxic 
pulm toxic-cough, dyspnea, 
 
Busulfan - correct an
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BMTCN questions & answers graded A+
- Exam (elaborations) • 6 pages • 2023
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BMTCNATG - correct answer anti t-cell globulin 
prevents GVHD, graft failure 
premeds: Tylenol, corticosteroids, Benadryl 
SE: hypotension, chills, rigors, fevers, pulmonary edema 
 
serum sickness - correct answer ATG 
myalgias, arthralgias, fever, rash, hand/facial edema 
give steroids 
 
BCNU (carmustine) - correct answer alkylating agent 
pre/post hydration 
SE: n/v, nephrotoxicity (elevated creat), pulmonary toxicity (pulmonary fibrosis, acute lung injury) 
infusion rx: feeling drunk, hypo...
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BMTCN ch.04 questions with complete solutions 2023/2024
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BMTCN ch.04preparative regimens - correct answer aka conditioning regiment 
part of HSCT when tx malignant diseases 
goal: eradicate residual disease and/or provide immunosuppression to prevent graft rejection 
prepare receipients bone marrow to accept new donor cells 
 
examples of chemo - correct answer cyclophosphamide 
busulfan 
etoposide 
cytarabine 
carmustine 
melphalan 
 
myeloablative regimens - correct answer lethal doses of chemo (usually includes alkylating agents) with or without TB...
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BMTCN ch.04(questions with verified solutions)2023/2024 updated to pass
- Exam (elaborations) • 3 pages • 2023
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BMTCN ch.04 
preparative regimens - correct answer aka conditioning regiment 
part of HSCT when tx malignant diseases 
goal: eradicate residual disease and/or provide immunosuppression to prevent graft rejection 
prepare receipients bone marrow to accept new donor cells 
 
examples of chemo - correct answer cyclophosphamide 
busulfan 
etoposide 
cytarabine 
carmustine 
melphalan 
 
myeloablative regimens - correct answer lethal doses of chemo (usually includes alkylating agents) with or without ...
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BMTCN Chapter 4 questions well answered rated A+
- Exam (elaborations) • 4 pages • 2023
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BMTCN Chapter 4BCNU - correct answer Carmustine 
Causes DNA Cross links and strand breaks 
Inhibits DNA repair 
Crosses blood/brain barrier 
Need pre/post hydration 
 
BCNU Side Effects - correct answer N/V 
Infusion reactions 
nephrotoxicity (increased Crea & BUN) 
pulmonary - cough, dyspnea, tachypnea 
acute lung injury - 10-30 days post infusion (tx w/ steroids; can be fatal) 
 
Busulfan - correct answer *Alkylating agent*-->cross-links DNA-->damages DNA 
 
Crosses blood brain barrier (...
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BMTCN Medication questions with 100% complete solutions 2023/2024
- Exam (elaborations) • 3 pages • 2023
- Available in package deal
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- $9.99
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BMTCN MedicationATG - correct answer Immune Suppressant. 
not recommended for reduced intensity regimens 
s/s pulm edema, hepatic dysfunction. 
Skin rash,joint pains(serum Sickness-TREATED WITH STEROIDS) 
Used before Allo for immunosuppression and later to treat GVHD. 
 
BCNU(carmustine) - correct answer nephro toxic 
pulm toxic-cough, dyspnea, 
 
Busulfan - correct answer neurotoxic SEIZURE-use levetiracetam 
hepatitis, VOD, 
rash, hairloss may be permanent 
pulmonary fibrosis 
premenopausal...
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