Pembrolizumab - Study guides, Class notes & Summaries
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The use of checkpoint inhibitors (e.g. pembrolizumab and ipilimumab) has been hailed as a major breakthrough in the treatment of cancer. Discuss why checkpoint inhibitors enhance anti-tumour responses and how they might be improved to be more efficacious
- Essay • 8 pages • 2023
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Immune checkpoint therapy is a new area of research which is ranked with surgery, chemotherapy radiation to improve survival rates against cancer. The immune checkpoint drug treatments specifically target the regulatory pathways within T cells to enhance anti-tumour responses, a shift from traditional therapies. Over the years there have been many drugs approved for treatments of different cancers, the first being ipilimumab for CTLA-4 blockade and nivolumab and pembrolizumab for PD-1 blockade (...
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Biochemical Engineering Questions and Answers
- Exam (elaborations) • 49 pages • 2024
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Biochemical Engineering Questions and 
Answers 
% transmission - CORRECT ANSWER-I(t)/I(o) x 100 
I(t): transmitted light in sample 
I(o): transmitted light (buffer alone) 
A = log(Io/It) = log(100% T) = 2 -log(%T) 
>60% natural proteins ____ - CORRECT ANSWER-glycosylated 
glycoproteins can be secreated, discharged in granules, shed from cell membranes or attach to 
cell surfaces 
- endothelial cells from a blood capillary with 'brush' of glycans 
- IgE, Eythropoetin, IgE, gelatinaseB, muc1,...
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