Pharm m3 - Study guides, Class notes & Summaries

1. More drugs metabolized by CYP3A4 greater than any other P450 enzyme = increased drug-drug interaction 2. Factors that regulate Css (serum conc), with this ADME is same to check maintenance dose = increase drug increase Css plasma levels 3. Induction of CYP450 Enzyme >>> increased # of enzymes, increased intrinsic? activity increased rate of metabolism = increase metabolic rate >>> decrease amount of purest? drug 4. IV drug 1st order kinetic Q 3hrs. 9 hrs later Cp (pla...

Maryville pharm Exam 4-Questions & Correct Answers What are important counseling points when administering antacids? - CORRECT ANSWERS-MUST BE SEPARATED FROM OTHER MEDS BY 1 HOUR; must be completely chewed and followed with water. Drink 2-4 ounces of water after taking the liquid antacid; can cause diarrhea (magnesium) or constipation (aluminum) How does loperamide (Imodium) treat diarrhea? (MOA) - CORRECT ANSWERS-(Opioid receptor agonists) Slows gastric motility and reduces fluid and elec...

APEA PHARM RESPIRATORY 1. When used in the treatment of chronic obstructive pulmonary disease (COPD), macrolides: inhibit bacterial protein synthesis. Macrolides such as erythromycin (Erytab) and azithromycin (Zithromax) inhibit bacterial protein synthesis and growth by blocking dissociation of peptidyl tRNA from ribosomes, causing RNA-dependent protein synthesis to arrest. Macrolides exert several immune-modulatory and anti-inflammatory effects. Penicillins inhib...

EXAM 1 Notes 1. More drugs metabolized by CYP3A4 greater than any other P450 enzyme = increased drug-drug interaction 2. Factors that regulate Css (serum conc), with this ADME is same to check maintenance dose = increase drug increase Css plasma levels 3. Induction of CYP450 Enzyme >>> increased # of enzymes, increased intrinsic? activity increased rate of metabolism = increase metabolic rate >>> decrease amount of purest? drug 4. IV drug 1st order kinetic Q 3hrs. 9 hrs...

1. More drugs metabolized by CYP3A4 greater than any other P450 enzyme = increased drug-drug interaction 2. Factors that regulate Css (serum conc), with this ADME is same to check maintenance dose = increase drug increase Css plasma levels 3. Induction of CYP450 Enzyme >>> increased # of enzymes, increased intrinsic? activity increased rate of metabolism = increase metabolic rate >>> decrease amount of purest? drug 4. IV drug 1st order kinetic Q 3hrs. 9 hrs later Cp (plasma...

NURS 531EXAM 1 Notes 1. More drugs metabolized by CYP3A4 greater than any other P450 enzyme = increased drug-drug interaction 2. Factors that regulate Css (serum conc), with this ADME is same to c heck maintenance dose = increase drug increase Css plasma levels 3. Induction of CYP450 Enzyme >>> increased # of enzymes, increased intrinsic? activity increased rate of metabolism = increase metabolic rate >>> decrease amount of purest? drug 4. IV drug 1st order kinetic Q 3hrs. 9 hr...

APEA PHARM RESPIRATORY 1. When used in the treatment of chronic obstructive pulmonary disease (COPD), macrolides: inhibit bacterial protein synthesis. Macrolides such as erythromycin (Erytab) and azithromycin (Zithromax) inhibit bacterial protein synthesis and growth by blocking dissociation of peptidyl tRNA from ribosomes, causing RNA-dependent protein synthesis to arrest. Macrolides exert several immune-modulatory and anti-inflammatory effects. Penicillins inhib...

NURS 531EXAM 1 Notes 1. More drugs metabolized by CYP3A4 greater than any other P450 enzyme = increased drug-drug interaction 2. Factors that regulate Css (serum conc), with this ADME is same to c hec k maintenance dose = increase drug increase Css plasma levels 3. Induction of CYP450 Enzyme > >> increased # of enzymes, increased intrinsic? activity increased rate of metabolism = increase metabolic rate >>> decrease amount of purest? drug 4. IV drug 1st order kinetic Q 3hrs. 9 ...