Analgesic opioid agonists - Study guides, Class notes & Summaries
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Opioid Pharmacology fully solved 2023/2024
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Opioid PharmacologyOpioid receptor subtypes - correct answer Mu, kappa, delta, (n=nociceptin) 
Mu, kappa & delta are G-i coupled GCPRs 
Mu is the predominant receptor 
Delta, kappa contribute to analgesia at *spinal level* 
 
Opioid receptor MOA - correct answer G-i coupled GCPRs 
- inhibition of AC 
1) decrease in VG Ca2+ current (decrease NT release -->analgesic effect) 
2) increased K+ conductance --> membrane hyperpolarization 
 
Distribution of opioid receptors in CNS, PNS - correct ...
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NCLEX PREP 2024 LATEST ACTUAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS ANSWERED 100% GUARANTEED PASS
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NCLEX PREP 2024 LATEST ACTUAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS ANSWERED 100% GUARANTEED PASS 
 
 
What is the therapeutic index? 
ratio of toxic dose to therapeutic dose (LD50/ED50) 
 
Low therapeutic index means increased risk for drug toxicity 
Drugs with narrow therapeutic index 
digoxin, lithium, warfarin 
What is the heparin antidote 
protamine sulfate 
Warfarin antidote 
Vitamin K 
Local anaesthetics drug class 
-caine 
 
Lidocaine 
Therapeutic class: Local anesthetic 
Indication: Pa...
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NR 565 NR565 Advanced Pharmacology Midterm Exam Questions with Accurate Responses
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NR 565 NR565 Advanced Pharmacology Midterm Exam Questions with Accurate Responses 
 
NR 565 NR565 Advanced Pharmacology Midterm Exam Questions with Accurate Responses 
 
During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? 
1st trimester (fetus most at risk d/t rapid growth) 
What is BEERS criteria? 
Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides 
What is the CYP450 (cytoch...
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Pharmacology Midterm notes ALL SOLUTION 2024 EDITION GUARANTEED GRADE A+
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half life 
Half-life (t½) is an important pharmacokinetic measurement. The metabolic half-life of a drug in vivo is the time taken for its concentration in plasma to decline to half its original level. Half-life refers to the duration of action of a drug and depends upon how quickly the drug is eliminated from the plasma. The clearance and distribution of a drug from the plasma are therefore important parameters for the determination of its half-life. 
B max 
The maximum amount of drug or radio...
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APCA 1 exam 2023 with 100% correct answers
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Alfaxalone - correct answer -IV anesthetic for dogs/cats, extra-label IM sedation for cats/small dogs (not large dogs because larger amount needed), no analgesia 
-res depression -- muscle tremors/hyperreactivity when alone 
-neuroactive steroid molecule 
 
Amlodipine Besylate PO - correct answer -Ca channel blocker (inhibits voltage-gated Ca channels in cardiac & vascular smooth muscle) 
-txt of systemic arterial hypertension 
-Caution using with: heart disease and hepatic dysfunction 
 
Apom...
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MPP Exam Questions With 100% Correct Answers
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MPP Exam Questions With 100% Correct Answers 
Understand the basic effects of nAChR ganglionic antagonists (which are no longer used) - 
Answer-Specifically block NAChR in the ganglia 
Hexamethonium (No CNS) 
Mecamylamine (Yes CNS) 
Effects are the opposite of the predominant tone (either symp or para sym effects) 
Effects of nAChR ganglionic antagonists in the arterioles, heart and GI -Answer-always opposite 
of predominant tone 
Arterioles: hypotention/ postural hypotention 
Heart: tachycardia...
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NR - 293 Pharmacology Exam 2: Units 3 and 4 Questions with 100% Correct Answers
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What are analgesic drugs? Correct Answer Pain killers that relieve pain without causing loss of consciousness. 
 
What are the 2 different class of analgesics? Correct Answer opioids analgesics and adjuvant analgesics 
 
What factors changes a person's perception of pain? Correct Answer Varies by attitude, environment, culture, ethnicity 
Past experience, anxiety, past experience, gender, general mental health 
 
A patient with bone cancer tells the nurse that he is in pain. The nurse knows tha...
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Pain Assessment and Nursing Management Exam 203 Questions with Verified Answers,100% CORRECT
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Pain Assessment and Nursing Management Exam 203 Questions with Verified Answers 
 
Define pain - CORRECT ANSWER An unpleasant sensory or emotional experience 
 Associated with actual or potential tissue damage 
 Or described in terms of such damage (International Association for the Study of Pain) 
 
whatever the person says it is, whenever the person says it is - McCaffery 
 
complex, multidimensional experience that can cause suffering and decreased QOL 
 
#1 symptom that brings individuals to...
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NR 293 Edapt Analgesic Drugs questions well answered graded A+ 2023/2024
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NR 293 Edapt Analgesic DrugsAnalgesic drugs are medications that relieve ______, but do not cause loss of consciousness. - correct answer Pain 
 
Opioids can be classified as mild agonists and strong agonists. __(1)___ agonists include codeine and hydrocodone, and ___(2)___ agonists include fentanyl, hydromorphone, meperidine, methadone, morphine and oxycodone. - correct answer Mild 
Strong 
 
1. Sudden onset that subsides with treatment. 
2. Skeletal muscle, ligament and joint pain. 
3. Level o...
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Portage Learning NURS 251 Pharmacology - Final Exam 2024
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Match the route of a drug administration to its indication: 
Rectal - Used if patient is unable to take oral route. 
Match the route of a drug administration to its indication: 
intramuscular - Used for drugs when high blood levels or rapid effects are needed. 
Match the route of a drug administration to its indication: 
intrathecal - For local effects within the spine 
Match the route of a drug administration to its indication: 
Inhalation - For local effects within the respiratory 
Match the r...
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