Gms 6504 - Study guides, Class notes & Summaries

GMS 6504 MODULE 1-3 Exam 1 (2024) Questions With Complete

Lipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equilibrium concentrations of dissolved substance in a two-phase system containing two largely immiscible solvents (water & octanol) - Log10(P) Improved Lipinski Parameters - ANSWER-1. Partition...

GMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectLipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equili...

GMS 6504 MODULE 1-3 EXAM 1 REVIEW QUESTIONS AND ANSWERS, RATED A+ What are System Independent Parameters? - -Affinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - -Number of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive Affinity is - -Thermokinetic propensity of drug to bind to receptor Based largely on ΔG Efficacy is - -Magnitude of change of receptor shape/function upon drug binding Base...

GMS 6504 MODULE 1-3 Exam 1 UPDATED Exam Questions and CORRECT Answers What are System Independent Parameters? - Correct ANSWER- Affinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - Correct ANSWER- Number of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive

GMS 6504 EXAM WITH VERIFIED ANSWERS

GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass What are System Independent Parameters? - Answer- Affinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - Answer- Number of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive Affinity is - Answer- Thermokinetic propensity of drug to bind to receptor Based largely on ΔG Efficacy is - Answer- Magnitude of change of receptor shape/function upon drug...

GMS 6504 Review Exam 2 Questions And Answers Rated A+ Which type of immune cells are most directly responsible for the killing of cancer cells during immunotherapy? Antigen presenting cells Cytotoxic T Lymphocytes Endothelial cells Dendritic cells ANS Cytotoxic T Lymphocytes Which type of antibody has a greater proportion of human sequence? Chimeric Humanized ANS Humanized Rituximab targets _________. HER2 CD20 CD33 CD3 ANS CD20

GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass What are System Independent Parameters? - Answer- Affinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - Answer- Number of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive Affinity is - Answer- Thermokinetic propensity of drug to bind to receptor Based largely on ΔG Efficacy is - Answer- Magnitude of change of receptor shape/function upon drug...

GMS 6504 MODULE 1-3 Exam 1 Accurate 100% What are System Independent Parameters? - ANSWER Affinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - ANSWER Number of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive Affinity is - ANSWER Thermokinetic propensity of drug to bind to receptor Based largely on ΔG Efficacy is - ANSWER Magnitude of change of receptor shape/function upon drug binding ...