Phase i trial aka - Study guides, Class notes & Summaries

CNPR NAPSR Exam Margin of safety - ANS the difference between the usual effective dose and the dose that induces severe or life threatening side effects Rights of drug administration - ANS right patient, right medication, right does, right route of administration, and right time of delivery Injection routes - ANS intramuscular, intrathecal, intravenous, subcutaneous intramuscular - ANS drugs given by direct injection into muscle tissue intrathecal - ANS needle is in...

CNPR, NAPSR Exam_Answered_Latest 2023+ Rated Drug Discovery • Unlike small molecule drugs (pharmaceuticals), large molecule drugs (biopharmaceuticals) are mainly protein-based o These protein-based drugs are similar to natural biological compounds found in human body or they're fragments that mimic active part of natural compounds Discovery of Pharmaceuticals commences w/ scanning hundreds of compounds, whether w/ actual materials (irrational approach) or virtual simulations (ratio...

Evidence-based Inquiry Week 1-3 Exam Questions and Complete Solutions EBP - Ans: "Evidence-based practice (EBP) is the process of integrating the best available research evidence, practitioner experience, and client values into practice decisions" Evidence-Based Practice - Ans: practitioner experience external evidence client's situation/values It is clear from this definition that evidence- based practice relies on practitioners' clinical expertise when applying research evidence t...

NBME practice exam #1 Questions Answered 100% correct 2023 Mitotic cyclin synthesis G2 phase Vitamin E def anemia Hemolytic anemia~ red antioxidants vs B12 def (megaloblastic macrocytic anemia) Hemolysis~ dec Hgb/hematocrit, inc LDH (normal MCV), and neurologic symptoms vs B12 def: dec Hgb/hematocrit, inc MCV, and neurologic symptoms (dorsal column) Volume of distribution Vd = (amount of drug in the body) / (plasma drug concentration) Achondroplasia Endochondria...

BPK 381 Final Exam 260 Questions with Verified Answers What is motivation? - CORRECT ANSWER The process that controls both the direction and strength of choice made by a person among alternative courses of actions -Vroom, 1964 What are the 5 critical concepts of motivation? - CORRECT ANSWER ∙Direction (positive or negative motivation) ∙Intensity (strong or moderate) ∙Persistence (how long does that behaviour change last, ex. hawthorne effect) ∙Behaviour (action from which we in...

PCCN Exam 120 Questions with Verified Answers Two days following a near-drowning accident, a pt is dyspneic, using accessory muscles, expectorating large amounts of secretions and reporting feeling of impending death. Changes to the assessment data include RR- 24 TO 36 CXR clear to bilateral diffuse infiltrates ABG 40% face mask or 100% non-rebreather mask pO2 120 mm Hg to 56 mm Hg pCO2 33 mmHg to 56 mmHg pH 7.42 to 7.35 HCO3 24 meq/L to 27 mEq/L Which of the ff do these changes mos...

Phase I Trial AKA correct answers Human Pharmacology Phase I Trial correct answers -Assess tolerance. -Define/describe PK and PD. -Explore drug metabolism and drug interactions, estimate activity. -Done in healthy volunteers.10 -100 people Phase II Trial AKA correct answers Therapeutic Exploratory Phase II Trial correct answers -Explore use for the targeted indication -estimate dosage for subsequent studies -provide basis for confirmatory study design endpoints, and methodologie...

Orthopedic NP Review Course Exam 591 Questions with Verified Answers Signs of inflammation - CORRECT ANSWER swelling, warmth, erythema, loss of function, tenderness Articular inflammation - CORRECT ANSWER Anatomic structure: synovium, cartilage, capsule (whithin the joint) Painful site: diffuse, deep Pain on movement: Active/passive, all planes Swelling: common Periarticular inflammation - CORRECT ANSWER Anatomic structure: Tendon, bursa, ligament, muscle, bone (outside the joint) P...

RNAS C Practice Test Review 437 Questions with Verified Answers A capacitor and resisitor in parallel - CORRECT ANSWER will have same voltage across since in parallel. if in series, voltage drops would occur they can be treated together If the absolute pressure of a gas is increased from 3 atm to 4 atm at constant volume, then the absolute temperature of the gas will increase by: A. 25%. B. 33%. C. 67%. D. 75% - CORRECT ANSWER B. Assuming the validity of the Ideal-Gas law, PV = n...

CISA Domain 3 Exam 113 Questions with Verified Answers Integrated Test Facility (ITF) - CORRECT ANSWER - Fictitious entity is created in LIVE environment - This technique allows auditor to open a dummy account - Auditor can enter dummy or test transactions and verify the processing and results of these transactions for correctness - Processed results and expected results are compared to verify that systems are operating correctly - Example: A dummy asset of $100,000/- is entered into syst...