Common cyp inhibitors Study guides, Class notes & Summaries

PHARM EXAM 1 (MSN) PNS: cholinergic receptors 1. nicotinic (N): all ANS ganglia and medulla 2. nicotinic (M): neuromuscular junction 3. muscarinic: PNS organs site of action: PNS rx -synapse -rx alters synaptic transmission (AcH) SNS: Adrenergic receptors -alpha 1, alpha 2, beta 1, beta 2 -also effects epi/norepi, dopamine breakdown of AcH -via AChE or MAO 1. AcH=reuptake into nerve cell 2. degraded by MAO 3. diffusion of waste out of cell sites where Rx act/influ...

Common CYP Inhibitors - Answer G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers - Answer Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate - Answer Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immunosuppressants: cyclospor...

Frontier PC 707 Advanced Pharmacology Final Safety Exam Understand and identify evidenced-based prescribing resources - Answer ️️ -ACOG, American Ca Society, National lung and heart instituete, EEP, Dynamed, Lexicomp, Sanford guide, lactamed **NO PDR Understand PLLR: Drugs in Pregnancy and Lactation: Improved Benefit-Risk information. - Answer ️️ -June 2015; 3 sections pregnancy-L&D, Lactation-nursing mothers; Fe/males of reproductive age; labeling updated as new information arrive...

RXPREP: KEY DRUGS, MNEMONICS, STUDY TIPS1 • HAZARDOUS DRUGS are: o Teratogenic o Carcinogenic o Genotoxic (damage the DNA and can cause cancer) o Have reproductive toxicity o Cause organ toxicity at low doses • Key hazardous drugs that require SPECIAL HANDLING to avoid toxicity to workers: o All pregnancy category X drugs, category D’s and a few C’s, and paroxetine, methotrexate, misoprostol, mifepristone, ribavirin o Antineoplastics (chemotherapeutics) o 5-alpha reductase inh...

NSG 6005 Pharm Week 5 Cardiovascular, Blood, Autonomic NS Study Guide Test. Assessments needed before prescribing HTN meds - CORRECT ANSWER BP (at least 3), head-toe, Labs (renal fxn & K+) Why are ACE Inhibitors good for diabetics? - CORRECT ANSWER improves insulin sensitivity and protects the kidneys What creatinine level would cause a change in dosage of ACE Inhibitors? - CORRECT ANSWER >2.5 What pathological change in heart failure is not addressed by ACE inhibitor? - CORRECT...

Pearl - Amide- vs. Ester-Type Anesthetics - Answer Amide-type anesthetics can be recognized by the "i" in their name before the"-caine" ending (e.g., lidocaine, bupivacaine, mepivacaine, ropivacaine). Ester-type anesthetics do not contain an "i" before the "-caine" ending (e.g., procaine, benzocaine, cocaine, tetracaine). Hypersensitivity to one type of drug in an anesthetic class, such as the ester-type procaine, does not confer cross-reactivity to drugs within the opposite anesth...

Mnemonics for NAPLEX (graded A+)already passed 2023Warfarin interactions - correct answer FLAMES o Fluconazole o Levofloxacin (really increase INR) o Amiodarone (worse interaction - decrease warfarin dose *by 50%*) o Metronidazole (decrease warfarin dose *by 1/3*) o Erythromycin (macrolides in general but this one is the worse) o Sulf-TMP CYP Inducers - correct answer PS PORCS o Phenytoin o Smoking o Phenobarbital o Oxcarbazepine (and eslicarbamazepine) o Rifampin o Carbama...

NR 546 Midterm Exam - Questions and Answers (Complete Solutions) What should the PMHNP consider when prescribing chemical restraints? -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? No. The client has been court-ordered to take the pre...

NR 660 Exam 2 Study Guide Latest Updated 2024. Know how to switch patients from one class of antidepressants to another STANDARD APPROACH Generally switching from one antidepressant to another is a 1-2 week cross taper. Goal is to prevent withdrawal symptoms, exacerbation of psychiatric illness or drug-drug interaction. At times one drug may be stopped abruptly and the next started the following day at equivalent dose if pharmacodynamic properties are similar—typically within the same dru...

Risk of Schizophrenia in monozygotic twins is? - ANSWER 46-50% Family hx risk of schizophrenia - ANSWER 10x risk with 1st degree relative brain changes in schizophrenia - ANSWER increase in ventricular volume (enlarged cerebral ventricles) Hippocampus volume decrease, 4% smaller Decreased electrical activity in frontal lobes Decrease glutamate and GABA release. Decreased total brain volume functional neuroimaging findings of schizophrenia - ANSWER Abnormal function of frontal corti...