Cytochrome p450 - Study guides, Class notes & Summaries

NR 546 WEEK 1 Quiz TO Week 6 Quiz with Accurate answers NR 546 WEEK 1 Quiz What should the PMHNP consider when prescribing chemical restraints? --*correct answer*---allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed How does reviewing the genetic makeup of a client help guide the PMHNP in selecting medication for clients? --*correct answer*---Genetic testing can assist b...

Pharmacokinetics (Ans- the study of what happens to a drug from the time of administration until the parent drug and all metabolites leave the body Pharmacokinetics concepts (Ans- absorption distribution metabolism excretion Flockhart Table (Ans- drug interactions that are mediated by cytochrome P450 enzymes comprehensive list of drugs and the interactions related to the cytochrome P450 system client factors that impact the effect of psychotropic medications (Ans- -age...

1. Pharmacokinetics ANS The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. 2. Pharmacodynamics ANS The study of what the drug does to the body 3. Factors Affecting Drug Absorption ANS Rate of dissolution Surface area Blood flow Lipid solubility pH partitioning 4. Factors Affecting Drug Distribution ANS Blood flow to tissues Ability to exit the vascular system Blood-brain barrier Protein-binding capacity 5. Xenobiotics ANS substances that a...

NR546 MIDTERM EXAM 2024 WITH 100% CORRECT ANSWERS What should the PMHNP consider when prescribing chemical restraints? - correct answer -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - correct answer No. The client has been c...

First Pass Metabolism CORRECT ANSWER GI Tract ---> Portal Circulation ---> Liver --->Metabolized ---> Systemic Circulation 1st pass metabolism lowers the amount of drug available. If high first-pass effect, mostly becomes inactivated and cannot be used, these meds cannot be given orally. Example: Insulin Drug Metabolism CORRECT ANSWER The most active organ is the LIVER (Cytochrome P450 enzyme system) Others are Kidneys, GI Tract, Lungs Coumadin and Bactrim CORRECT ANSW...

Pharmacology and Pharmacotherapeutics in Advanced Nursing Practice NGR6172 Chapter 1: Prescriptive Authority and Role Implementation: Tradition vs Change o Primary Care is provided by clinicians who address "personal health care needs, developing a sustained partnership with patient, and practicing in the context of family and community."  Prevention, Diagnosis, Prescription, Treatment  Assess health status.  Promote healthy lifestyles.  Identifying/diagnosing normal/abnorm...

NURS 6630 Midterm Exam Test Bank Questions and Answers 100%Correct NEW 2023. Question 1 1 out of 1 points A noncompliant patient states, “Why do you want me to put this poison in my body?” Identify the best response made by the psychiatric-mental health nurse practitioner (PMHNP). Answer: C. “Most medications that work in the brain will result in restoring an imbalance of one or more neurotransmitters that your body already produces helping to alleviate your symptoms .” Question...

CU NR 546 Questions and Answers with Complete Solutions How can genetic testing aid the PMHNP in developing a personalized treatment plan for patients? A. By identifying specific genetic markers for mental health disorders B. By providing information on how clients may respond to certain psychotropic medications and break down and metabolize medications based on the cytochrome P450 system C. By identifying genetic links to certain medications D. By determining the client's ancestr...

NR 565-ADVANCED PHARMACOLOY MIDTERM WITH QUESTIONS AND WELL VERIFIED ANSWERS [GRADED A+] ACTUAL EXAM 100%] During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? - ANS---1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? - ANS---Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides CYP450 inducers - ANS---Speed up metabolism of drugs (drug is cleared faster...

NRNP 6566 Midterm Study Guide 2024 with Complete Solutions. Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormon...