Bme347 - Study guides, Class notes & Summaries

Why develop regenerative engineering technologies - To optimize naturally occurring regenerative mechanisms what are 2 problems with naturally occurring regenerative mechanisms - Timing: cell regen takes 3-5 days effectiveness: level of regen (ex. too much fibroblast regen/not enough cardiomyocyte regen) What is atherosclerosis? - when a branch of the coronary artery becomes blocked by an atheroma (buildup of plaque/leuokcytes/SMCs/endothelial cells) embolus - piece of atheroma that de...

why does regeneration happen - Injury/insults (physical factors, chemical factors, biological factors) physical factors that could happen to a cell - temperature, radiation, shear stress chemical factors that could happen to a cell - toxins, signaling molecules being present/absent biological factors that could happen to a cell - ROS, oxidants, O2- cause DNA damage what is regenerative engineering - discipline to understand natural regenerative process in injury and disorders to deve...

These are detailed notes of the Foundations of Regenerative Engineering course at Northwestern University and they cover all the material discussed in class. This course focuses on molecular, cellular, and tissue regeneration. The student who wrote the notes got an A in the class.