Cmmb403 midterm - Study guides, Class notes & Summaries

Cmmb403 midterm exam with 100% correct answers Holt-Oram - answer____ syndrome is a human disease w a developmental basis that causes forelimb and heart defects where radius is missing and theres a hole btw ventricles so oxygenated and deoxygenated blood mixes. It is caused by a mutation of ONE copy of the TBX5 gene that codes for a transcription factor TBX5 - answerthe transcription factor that is mutated in Holt-Oram syndrome - is expressed in the forelimb and the heart (NOT the hind li...

Cmmb403 midterm exam with 100% correct answers Holt-Oram - answer____ syndrome is a human disease w a developmental basis that causes forelimb and heart defects where radius is missing and theres a hole btw ventricles so oxygenated and deoxygenated blood mixes. It is caused by a mutation of ONE copy of the TBX5 gene that codes for a transcription factor TBX5 - answerthe transcription factor that is mutated in Holt-Oram syndrome - is expressed in the forelimb and the heart (NOT the hind li...

Holt-Oram - ____ syndrome is a human disease w a developmental basis that causes forelimb and heart defects where radius is missing and theres a hole btw ventricles so oxygenated and deoxygenated blood mixes. It is caused by a mutation of ONE copy of the TBX5 gene that codes for a transcription factor TBX5 - the transcription factor that is mutated in Holt-Oram syndrome - is expressed in the forelimb and the heart (NOT the hind limb) one (haploinsufficient) - one/two copy/copies oft he...

The Drosophila embryo forms repeated morphological units called ________. - segments How many segments total? Thoracic? Abdominal? - 11 total 3 thoracic 8 abdominal Each abdominal segment on the ventral side of the larva is characterized by _________ (which point posteriorly) and a ___________. - anterior denticles posterior naked region What did Christiane Nüsslein-Volhard and Eric Wieschaus do? - they screened thousands of embryos for patterning defects How do they identify genes o...