Ngr 6172 stuvia - Study guides, Class notes & Summaries
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NGR 6172 Pharm EX1 Questions With Correct Answers
- Exam (elaborations) • 4 pages • 2024
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Aspirin- MOA - Answer Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) 
 
Decrease prostaglandin and thromboxane A2 production 
 
Plavix (clopidogrel) -MOA - Answer Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation 
 
Boxed warning of Plavix - Answer conversion to active metabolite require (CYP 450 2C19) 
Poor metabolizers - higher CV events 
 
Plavix- avoid to take with what - Answer 2c19 inhibitors (omeprazole, esomeprazole) 
increased bleed 
 
pos...
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NGR 6172 Diabetes drugs Exam Questions With Correct Answers
- Exam (elaborations) • 3 pages • 2024
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MOA for insulin - Answer Transports glucose across cell membrane 
 
MOA for sulfonurias (glipizide, Glucotrol) - Answer Stimulates insulin secretion 
 
MOA for biguanides (metformin) - Answer Reduce hepatic glucose production 
 
MOA for Thiazolidinediones (Actos) - Answer Increases peripheral insulin sensitivity 
 
MOA for Secretagogues or meglitinides (nateglinide, prandin) - Answer short-term beta cell timulation 
 
MOA for alpha-glucosidase inhibitors (acarbose, Precose) - Answer Prevent brea...
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