Nucleoside analogues - Study guides, Class notes & Summaries

Predictors of PDL1/PD1 inhibitor response Presence of tumor CD8 cell infiltration High cancer genome burden High levels of cancer PD-L1 expression (PD1 is on the cytotoxic T cell) Ipilimumab CTLA4 inhibitor Nivolumab PD-1 inhibitor Regorafenib VEGF inhibitor Bevacizumab Monoclonal antibody against VEGF-A. Inhibits angiogenesis. Pembrolizumab PD-1 inhibitor Atezolizumab PD-L1 inhibitor Avelumab PD-L1 inhibitor Durvalumab PD-L1 ...

Antiviral Chemistry & Chemotherapy’s current antiviral agents FactFile (2nd edition): DNA viruses Hugh J Field1 * and Erik De Clercq2 1Department of Veterinary Medicine, University of Cambridge, Cambridge, UK 2Rega Institute for Medical Research, Leuven, Belgium *Corresponding author: E-mail: Although most of the recent attempts to develop new antiviral agents have been focussed on RNA viruses (in particular, HIV and hepatitis C virus), a few new compounds are now awaiting thei...

Predictors of PDL1/PD1 inhibitor response Presence of tumor CD8 cell infiltration High cancer genome burden High levels of cancer PD-L1 expression (PD1 is on the cytotoxic T cell) Ipilimumab CTLA4 inhibitor Nivolumab PD-1 inhibitor Regorafenib VEGF inhibitor Bevacizumab Monoclonal antibody against VEGF-A. Inhibits angiogenesis. Pembrolizumab PD-1 inhibitor Atezolizumab PD-L1 inhibitor Avelumab PD-L1 inhibitor Durvalumab PD-L1 inhibitor Cemiplimab PD-1 inhibitor fo...

Anti-Viral Nucleoside Analogues (AZT) - correct answer --> Viral reverse transcriptase inhibitors Nucleoside analogues---> -Molecules that act like nucleosides in DNA synthesis. Include a range of antiviral products used to prevent viral replication in infected cells. Anti-Viral Nucleoside Analog--> 1) Azidothymidine (AZT) Zidovudine--> -It is a thymidine analog. AZT is identical to deoxythymidine in every way except at the ...

AMCB study material Question and answers correctly solved 2023/2024 Methergine - correct answer 0.2 mg IM May repeat in 5 min Then q 2-4 hr Onset of action: 2-5 min Peaks @ 20-30 min *CI in HTN/pre-e* Hemabate - correct answer 250 mcg IM May repeat q 15-90 min, x 8 doses if needed Peaks @ 30 min *CI in asthma* Misoprostol (Cytotec) - correct answer 600-800 mcg SL or 800-1000 mcg per rectum x 1 dose Onset of action: 3-5 min Peaks @ 40-60 min (rectal); @ 30 min (SL) ...

REGIS NU641 Pharmacology Exam 2 Study Guide 2023 Infectious Disease (35%) Resistance factors: d/t recent use of abx, over prescription of broad spectrum abx, <2yo & >65yo tend to have more abx resistance, day care center attendees, exposure to young kids, multiple comorbids, immunosuppression (b/c tx’d w/ abx frequently) refer to local lab’s antibiogram to decide tx- identifies local resistance patterns* Antibiotic Classes – focus on what’s treated in Primary Care / Outp...

REGIS NU641 Pharmacology Exam 2 Study Guide 2023 Infectious Disease (35%) Resistance factors: d/t recent use of abx, over prescription of broad spectrum abx, <2yo & >65yo tend to have more abx resistance, day care center attendees, exposure to young kids, multiple comorbids, immunosuppression (b/c tx’d w/ abx frequently) refer to local lab’s antibiogram to decide tx- identifies local resistance patterns* Antibiotic Classes – focus on what’s treated in Primary Care / Outp...

REGIS NU641 Pharmacology Exam 2 Study Guide 2023 Infectious Disease (35%) Resistance factors: d/t recent use of abx, over prescription of broad spectrum abx, <2yo & >65yo tend to have more abx resistance, day care center attendees, exposure to young kids, multiple comorbids, immunosuppression (b/c tx’d w/ abx frequently) refer to local lab’s antibiogram to decide tx- identifies local resistance patterns* Antibiotic Classes – focus on what’s treated in Primary Care / Outp...

Immunotherapy / Chemotherapy Exam With 100% Verified And Correct Answers 2024

Grapefruit Juice - Answer CYP450 inhibitor PCN contraindications - Answer hx type 1 PCN allergy caution in hx of cephalosporin allergy PCN can ___________ the effects of warfarin - Answer increase (increase bleeding risk) Tetracycline contraindications - Answer pregnancy lactation children under 8 they bind to the calcium in bones and teeth resulting in yellow or brown discoloration and hypoplasia of the tooth enamel may also occur. Tetracyclines may decrease the effectiveness...