Snase - Study guides, Class notes & Summaries

Comprehensive Biochemistry and Molecular Biology Notes Key Concepts Covered: 1. Staphylococcus aureus Nuclease (SNase) Functionality: - **Role in Biofilm Formation**: SNase cleaves extracellular DNA in neutrophil extracellular traps, utilizing the DNA as a scaffold for biofilm formation. - **Calcium as a Cofactor**: Ca2+ activates water molecules to cleave phosphodiester bonds, optimized for extracellular conditions with a higher pH and calcium concentration. 2. Blue Plate Assay...