Use of isostere - Study guides, Class notes & Summaries

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BPS 2110 Midterm 2 Exam Questions And Correct Answers
  • BPS 2110 Midterm 2 Exam Questions And Correct Answers

  • Exam (elaborations) • 39 pages • 2024
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BPS2110 Midterm 2 Exam Questions and Answers 100% Solved
  • BPS2110 Midterm 2 Exam Questions and Answers 100% Solved

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  • BPS2110 Midterm 2 Exam Questions and Answers 100% Solved use of isostere - functional group replacements isostere - groups of atoms with similar sterics and electronics. give similar biological activity classical isostere - atoms or groups that have the same valency and similar size help determine if groups are important for binding EXAMPLE: OH = F, Cl, SH, NH2, CH3 Non-classical isosteres - atoms or groups that have similar chemical properties (look for similar pka values) differ in ...
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