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Antibiotic Discovery and Targets What are the two types of antibiotics and how are they different? - Answer- - Bacteriostatic antibiotics: block bacterial growth - Bacteriocidal antibiotics: kill bacteria Give examples of bacteriostatic antibiotics - Answer- - Tetracyclines - Sulphonamides - Chloramphenicol Give an example of a bacteriocidal antibiotic - Answer- Penicillins Describe the circumstances leading to the discovery of penicillin - Answer- - It was discovered by Ernest Du...

L3 - Antibiotic discovery Before penicillin - Answer- Paul Ehrlich - 'magic-bullet' for treatment 1904: Systematic, large scale search for drugs active against syphilis - found compound 606 (arsphenamine derivative, salvarsan) - unknown mechanism Systematic search style later used by Bayer in discovery of Sulfa drugs (1932) and release of prontosil (1936) Discovery of penicillin (dawn of the antibiotic age) - Answer- 1928: Accidental discovery by Flemming BUT... Low yie...

ANTIBIOTIC DISCOVERY Definition of antibiotic - Answer- A chemical of natural /synthetic origin which inhibits microorganisms within a host organism and an acceptable toxicity profile on the host Example of an antimicrobial that isn't an antibiotic - Answer- Bleach- not an antibiotic because its toxicity profile on host isn't acceptable What is the Waksman Platform, used in the 1940s-1960s golden era of antibiotic discovery - Answer- Systematic screening of soil samples against ba...

ANTIBIOTIC DISCOVERY What were the leading causes of death before 1930 - Answer- tuberculosis, pneumonia, and gas gangrene (in WWI) what microorganism causes gangrene? What is its habitat and what are its distinguishing features - Answer- Clostridium perfringens -anaerobic, endospore forming -soil/enteric microorganism -causes myonecrosis to muscle tissue -produces gas and exotoxin (alpha toxin) -WWI ()= gas gangrene caused lots of deaths what scientist was in search of the univers...

Employee Registration Manual: GA Pest Control Exam Why was the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) created? - Answer- to regulate the registration and labeling of pesticides. What government agency oversees the implementation of the FIFRA? - Answer- The EPA- Environmental Protection Agency What does the Endangered Species Act (1973) have to do with pest control? - Answer- ensure that using registered pesticides would not harm Endangered Species Tolerance level...

Georgia Pest Control Registration Exam GSPCC - Answer- Georgia Structural Pest Control Commission GDA - Answer- Georgia Department of Agriculture FIFRA - Answer- Federal Insecticide, Fungicide, and Rodenticide Act 1947 Regulate the registration and labeling of pesticides. Amended in 1972 to include classification systems for types of pesticides and created requirements for: -Certification of applicators authorized to apply pesticides -Safety of workers using pesticides -Protection ...

GA PEST EXAM anticoagulant - Answer- prevents blood clotting anticoagulant - first generation - Answer- generally require bait consumption over several feedings (days) in order to get lethal dose anticoagulant - second generation - Answer- lethal after single ingestion FIFRA - Answer- Federal Insecticide, Fungicide, and Rodenticide Act FQPA - Answer- Food Quality Protection Act of 1996 Carries the same enforcement weight as the actual label provided on the pesticide container -...

Math Ga Milestones A store sells markers in packs of 12 and pencils in packs of 5. Lanier wants to buy an equal number of markers and pencils. What is the MINIMUM number of markers Lanier would have to buy? - Answer-60 What is the greatest common factor of 30, 42, and 48? - Answer-6 Which expression is equivalent to 16 + 56? 2(14 + 54) 4(4 + 12) 7(2 + 8) 8(2 + 7) - Answer-8(2 + 7) Miley drove 288 miles in 4 hours. If she continues at the same rate, how far would she drive in 8 hours?...

8th Grade GSE Milestones: Social Studies Smallest of the 5 regions - Answer-The Appalachian Plateau Most populated region - Answer-Piedmont Contains the capital city of GA - Answer-Piedmont Receives the highest annual rainfall - Answer-Blue Ridge largest freshwater march in GA - Answer-Okefenokee Swamp Represents the border between Georgia and Alabama, one of Georgia's most important rivers. - Answer-Chattahoochee River Serves as protection to Georgia's mainland from i...

Ga milestones US history eoc Treaty of Paris 1783 - Answer-Treaty Between England and the Colonies , formally ended the french and indian war Proclamation of 1763 - Answer-Americans were forbidden from settling beyond the Appalachian mountains to limit conflicts with Indians Stamp Act - Answer-law that taxed printed goods and the sons of liberty were formed intolerable acts - Answer-closed port of Boston as a punishment for the Boston tea party Common Sense by Thomas Paine - Answe...