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NBME 27 Recent Questions and Answers with Excellent Rationale
Q: AV fistulas result in what change to the heart dynamics? 
Ans: This is an abnormal connection between the atria and ventricles, 
resulting in increased blood flowing from the atria to the ventricles. increased 
CO results (until high output heart failure ensues, but that takes time) 
Q: 
Pierre Robin Sequence 
Ans: Mandibular hypoplasia, glossoptosis, cleft soft palate. W/ FAS or 
Edwards. 
Q: 
What is the main regulator of serum osmolality? 
Ans: ADH (vasopressin) 
re...
- Exam (elaborations)
- • 18 pages •
Q: AV fistulas result in what change to the heart dynamics? 
Ans: This is an abnormal connection between the atria and ventricles, 
resulting in increased blood flowing from the atria to the ventricles. increased 
CO results (until high output heart failure ensues, but that takes time) 
Q: 
Pierre Robin Sequence 
Ans: Mandibular hypoplasia, glossoptosis, cleft soft palate. W/ FAS or 
Edwards. 
Q: 
What is the main regulator of serum osmolality? 
Ans: ADH (vasopressin) 
re...

NBME 27 Recent Q and A Questions and Answers with Excellent Rationale
NBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent Rationale
- Exam (elaborations)
- • 55 pages •
NBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent RationaleNBME 27 Recent Q and A Questions 
and Answers with Excellent Rationale

NBME 26 ;~) Recent Questions and Answers with Excellent Rationale
Q: Paresthesias 
Ans: abnormal sensation (e.g., tingling, prickling, "pins and needles") 
Q: 
placenta accreta 
Ans: A rare disorder in which the placenta is directly adherent to the 
myometrium (without penetrating) instead of the decidua basalis. Results in 
delayed separation and/or placental retention as well as postpartum 
hemorrhage. The most important risk factors for placenta accreta are a 
previous C-section and placenta previa. -risk factors include: prior uterine i...
- Exam (elaborations)
- • 54 pages •
Q: Paresthesias 
Ans: abnormal sensation (e.g., tingling, prickling, "pins and needles") 
Q: 
placenta accreta 
Ans: A rare disorder in which the placenta is directly adherent to the 
myometrium (without penetrating) instead of the decidua basalis. Results in 
delayed separation and/or placental retention as well as postpartum 
hemorrhage. The most important risk factors for placenta accreta are a 
previous C-section and placenta previa. -risk factors include: prior uterine i...

NBme 26 Recent Questions and Answers with Excellent Rationale
Q: Lab findings of autoimmune hemolytic anemia (both warm and cold), 
Ans: + direct combs test (detects RBCS with IgG or C3b), indirect coombs, 
hemoglobinuria, decreased haptoglobin 
normocytic anemia, increased reticulocyte count, spherocytes, 
unconjugated hyperbilirubinemia 
Q: 
Following MI a common cause of mitral regurgitation is? 
Ans: Rupture of a papillary muscle and associated chordae tendinea 
Q: 
A low gamma (Y) fraction on proteins electrophoresis indicates wha...
- Exam (elaborations)
- • 52 pages •
Q: Lab findings of autoimmune hemolytic anemia (both warm and cold), 
Ans: + direct combs test (detects RBCS with IgG or C3b), indirect coombs, 
hemoglobinuria, decreased haptoglobin 
normocytic anemia, increased reticulocyte count, spherocytes, 
unconjugated hyperbilirubinemia 
Q: 
Following MI a common cause of mitral regurgitation is? 
Ans: Rupture of a papillary muscle and associated chordae tendinea 
Q: 
A low gamma (Y) fraction on proteins electrophoresis indicates wha...

NBME 26 Recent Questions and Answers with Excellent Rationale
Q: serum electrophoresis 
Ans: First peak is albumin 
alpha 1 globulins = alpha antitrypsin, alpha 1 antichymotrypsin, TBG, 
alpha 2 globulins = haptoglobulin, macroglobulin, ceruloplasmin, TBG, protein 
C, angiotensinogen 
beta = beta 2 microglobin, plasminogen, angiostatins, SHBG, transferrin 
gamma = Ig 
Q: 
serum electrophoresis in multiple myeloma 
Ans: gamma spike 
Q: 
serum electrophoresis blurring beta 2 and gamma regions 
Ans: increased CRP 
increased IgA 
a...
- Exam (elaborations)
- • 18 pages •
Q: serum electrophoresis 
Ans: First peak is albumin 
alpha 1 globulins = alpha antitrypsin, alpha 1 antichymotrypsin, TBG, 
alpha 2 globulins = haptoglobulin, macroglobulin, ceruloplasmin, TBG, protein 
C, angiotensinogen 
beta = beta 2 microglobin, plasminogen, angiostatins, SHBG, transferrin 
gamma = Ig 
Q: 
serum electrophoresis in multiple myeloma 
Ans: gamma spike 
Q: 
serum electrophoresis blurring beta 2 and gamma regions 
Ans: increased CRP 
increased IgA 
a...

NBME 25 Recent Questions and Answers with Excellent Rationale
Q: Large pressure gradient between left ventricle and aorta during systole 
Ans: aortic stenosis (calcification) 
Q: 
Hyperacute transplant rejection is what type of hypersensitivty rxn 
Ans: type 2 - pre existant recipient antibodies react to donor antigen 
Q: 
acute transplant rejection is what type of hypersensitivity rxn 
Ans: type 4- T cell mediated 
OR 
humoral: similar to hyperacute except antibodies form after transplant 
Q: 
which type of transplant rejecti...
- Exam (elaborations)
- • 24 pages •
Q: Large pressure gradient between left ventricle and aorta during systole 
Ans: aortic stenosis (calcification) 
Q: 
Hyperacute transplant rejection is what type of hypersensitivty rxn 
Ans: type 2 - pre existant recipient antibodies react to donor antigen 
Q: 
acute transplant rejection is what type of hypersensitivity rxn 
Ans: type 4- T cell mediated 
OR 
humoral: similar to hyperacute except antibodies form after transplant 
Q: 
which type of transplant rejecti...

NBME 25 Recent Questions and Answers with Excellent Rationale
Q: what is nonpurging type bulimia nervosa? BMI? 
Ans: involves cycles of uncontrollable eating and compensatory behaviors 
that occur at least one week over three months or more; patients typically 
have normal BMI and rather than engaging in purging behaviors such as 
vomiting, they typically will fast or intensely exercise (purge = vomit) 
Q: 
Describe electrolyte imbalances in anorexia nervosa (binge 
eating/purging type) 
Ans: hypochloremic metabolic alkalosis from vomiting --...
- Exam (elaborations)
- • 18 pages •
Q: what is nonpurging type bulimia nervosa? BMI? 
Ans: involves cycles of uncontrollable eating and compensatory behaviors 
that occur at least one week over three months or more; patients typically 
have normal BMI and rather than engaging in purging behaviors such as 
vomiting, they typically will fast or intensely exercise (purge = vomit) 
Q: 
Describe electrolyte imbalances in anorexia nervosa (binge 
eating/purging type) 
Ans: hypochloremic metabolic alkalosis from vomiting --...

NBME 27 Recent Questions and Answers with Excellent Rationale
Q: Breathing in gas mixture with low PO2 
Ans: Hypoxemia induces hyperventilation —> Respiratory alkalosis 
Q: 
Effect of arteriovenous fistulas on right atrial pressure and CO 
Ans: Increase in right atrial pressure d/t increase in preload 
Increase in CO d/t Frank Starling mechanics 
Q: 
Micrognathia, glossoptosis, mandibular cleft, short palate; Dx and 
pharyngeal arch 
Ans: Pierre Robin syndrome; 1st pharyngeal arch 
Downward displacement of tongue leads to airway ...
- Exam (elaborations)
- • 13 pages •
Q: Breathing in gas mixture with low PO2 
Ans: Hypoxemia induces hyperventilation —> Respiratory alkalosis 
Q: 
Effect of arteriovenous fistulas on right atrial pressure and CO 
Ans: Increase in right atrial pressure d/t increase in preload 
Increase in CO d/t Frank Starling mechanics 
Q: 
Micrognathia, glossoptosis, mandibular cleft, short palate; Dx and 
pharyngeal arch 
Ans: Pierre Robin syndrome; 1st pharyngeal arch 
Downward displacement of tongue leads to airway ...

Medications for Asthma and COPD Recent Questions and Answers with Excellent Rationale
Q: Long acting beta agonists (LABA) 
Ans: salmeterol, aformoterol, formoterl 
Q: 
short-acting beta agonists (SABA) 
Ans: albuterol, levalbuterol, metaproterenol 
Q: 
long-acting muscarinic antagonist (LAMA) 
Ans: Tiotropium (Spiriva) 
Q: 
Short-acting muscarinic antagonist (SAMA) 
Ans: Ipratropium (available alone or in combo with albuterol) 
Q: 
Corticosteroids 
Ans: beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, 
mometasone, traimcinol...
- Exam (elaborations)
- • 19 pages •
Q: Long acting beta agonists (LABA) 
Ans: salmeterol, aformoterol, formoterl 
Q: 
short-acting beta agonists (SABA) 
Ans: albuterol, levalbuterol, metaproterenol 
Q: 
long-acting muscarinic antagonist (LAMA) 
Ans: Tiotropium (Spiriva) 
Q: 
Short-acting muscarinic antagonist (SAMA) 
Ans: Ipratropium (available alone or in combo with albuterol) 
Q: 
Corticosteroids 
Ans: beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, 
mometasone, traimcinol...

Medications for Asthma and COPD Recent Questions and Answers with Excellent Rationale
Q: Long acting beta agonists (LABA) 
Ans: salmeterol, aformoterol, formoterl 
Q: 
short-acting beta agonists (SABA) 
Ans: albuterol, levalbuterol, metaproterenol 
Q: 
long-acting muscarinic antagonist (LAMA) 
Ans: Tiotropium (Spiriva) 
Q: 
Short-acting muscarinic antagonist (SAMA) 
Ans: Ipratropium (available alone or in combo with albuterol) 
Q: 
Corticosteroids 
Ans: beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, 
mometasone, traimcinol...
- Exam (elaborations)
- • 14 pages •
Q: Long acting beta agonists (LABA) 
Ans: salmeterol, aformoterol, formoterl 
Q: 
short-acting beta agonists (SABA) 
Ans: albuterol, levalbuterol, metaproterenol 
Q: 
long-acting muscarinic antagonist (LAMA) 
Ans: Tiotropium (Spiriva) 
Q: 
Short-acting muscarinic antagonist (SAMA) 
Ans: Ipratropium (available alone or in combo with albuterol) 
Q: 
Corticosteroids 
Ans: beclomethasone, budesonide, ciclesonide, flunisolide, fluticasone, 
mometasone, traimcinol...