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BASICS OF EPIDEMIOLOGY
BASICS OF 
EPIDEMIOLOGY 
Public Health 
 • The science and art of preventing disease, prolonging 
life and promoting health through organized 
community efforts 
Public health core functions 
 • Assessment 
 • The assessment & monitoring of the health of communities 
and populations at risk to identify health problems and 
priorities 
 • Policy Development 
 • The formulation of public policies designed to solve 
identified local and national health problems and priorities 
 • ...
- Exam (elaborations)
- • 17 pages •
BASICS OF 
EPIDEMIOLOGY 
Public Health 
 • The science and art of preventing disease, prolonging 
life and promoting health through organized 
community efforts 
Public health core functions 
 • Assessment 
 • The assessment & monitoring of the health of communities 
and populations at risk to identify health problems and 
priorities 
 • Policy Development 
 • The formulation of public policies designed to solve 
identified local and national health problems and priorities 
 • ...
BASICS OF CT SCAN NEUROIMAGING
Basic rule: Image orientation 
 2 
 By convention, the right side of 
the brain CT scan is on the left 
of the reader and it should be 
labelled as such! 
 Brain CT images are read as 
if you are viewing the patient 
from the feet thus their right 
side of the brain is to your 
left and vice vasa. 
 The anterior part of the head 
is at the top of the image. 
 9/26/2024 
 A.N. Malik, Department of Human Anatomy, JKUAT. 
The 3 basic densities/shades of grey 
 3 
 Isodense: ...
- Exam (elaborations)
- • 61 pages •
Basic rule: Image orientation 
 2 
 By convention, the right side of 
the brain CT scan is on the left 
of the reader and it should be 
labelled as such! 
 Brain CT images are read as 
if you are viewing the patient 
from the feet thus their right 
side of the brain is to your 
left and vice vasa. 
 The anterior part of the head 
is at the top of the image. 
 9/26/2024 
 A.N. Malik, Department of Human Anatomy, JKUAT. 
The 3 basic densities/shades of grey 
 3 
 Isodense: ...
BASIC PAEDIATRIC PROTOCOLS
Facilities must have basic equipment and drugs in stock at all times, 
and adequate staff skilled in paediatric care. 
 Sick children coming to hospital must be immediately triaged, 
assessed and if necessary, provided with emergency treatment as 
soon as possible. 
 Assessment of diagnosis and illness severity must be thorough and 
treatment must be carefully planned. All stages should be accurately 
and comprehensively documented. 
 The protocols provide a minimum standard and safe approa...
- Class notes
- • 100 pages •
Facilities must have basic equipment and drugs in stock at all times, 
and adequate staff skilled in paediatric care. 
 Sick children coming to hospital must be immediately triaged, 
assessed and if necessary, provided with emergency treatment as 
soon as possible. 
 Assessment of diagnosis and illness severity must be thorough and 
treatment must be carefully planned. All stages should be accurately 
and comprehensively documented. 
 The protocols provide a minimum standard and safe approa...
History of Microbiology
History of Microbiology 
Man kind has always been affected by diseases which were 
originally believed to be visitations by the gods and meant to punish 
evil doers. 
Hippocratus, father of medicine, observed that ill health resulted due 
to changes in air, winds, water, climate, food, nature of soil and 
habits of people. 
Varro (117-26 BC)said a theory that disease was caused by 
animated particles invisible to naked eye but which were carried in 
the air through the mouth and nose in...
- Class notes
- • 444 pages •
History of Microbiology 
Man kind has always been affected by diseases which were 
originally believed to be visitations by the gods and meant to punish 
evil doers. 
Hippocratus, father of medicine, observed that ill health resulted due 
to changes in air, winds, water, climate, food, nature of soil and 
habits of people. 
Varro (117-26 BC)said a theory that disease was caused by 
animated particles invisible to naked eye but which were carried in 
the air through the mouth and nose in...
Bacillus
Bacillus 
General Characteristics of Bacillus 
 ~ 60 species; Gram-positive or Gram-variable bacilli 
 • Large (0.5 x 1.2 to 2.5 x 10 um) 
 • Most are saprophytic contaminants or normal flora 
 • Bacillus anthracis is most important member 
 Produce endospores 
 Aerobic or facultatively anaerobic 
 Catalase positive (most) 
 • Rapidly differentiates from Clostridium 
 Bacillus spp. are ubiquitous 
 • Soil, water, and airborne dust 
 • Thermophilic (< 
 75°C) an...
- Class notes
- • 42 pages •
Bacillus 
General Characteristics of Bacillus 
 ~ 60 species; Gram-positive or Gram-variable bacilli 
 • Large (0.5 x 1.2 to 2.5 x 10 um) 
 • Most are saprophytic contaminants or normal flora 
 • Bacillus anthracis is most important member 
 Produce endospores 
 Aerobic or facultatively anaerobic 
 Catalase positive (most) 
 • Rapidly differentiates from Clostridium 
 Bacillus spp. are ubiquitous 
 • Soil, water, and airborne dust 
 • Thermophilic (< 
 75°C) an...
Nucleic	Acids
Nucleic	Acids	 
	 
Nucleic	acids	 
• Polymers	of	nucleo des	are	termed	polynucleo des	or	nucleic	 
acids,	be er	known	as	DNA	and	RNA.	 
• 	Each	nucleic	acid	is	made	from	just	four	different	nucleo des.	 
• 	RNA	contain	the	bases	adenine,	cytosine,	guanine,	and	uracil	 
• 	DNA	contain	adenine,	cytosine,	guanine,	and	thymine.	 
• Polymeriza on	involves	the	phosphate	and	sugar	groups	of	the	 
nucleo des,	which	become	linked	by	phosphodiester	bonds	 
• primary	role:	act	as	ca...
- Class notes
- • 52 pages •
Nucleic	Acids	 
	 
Nucleic	acids	 
• Polymers	of	nucleo des	are	termed	polynucleo des	or	nucleic	 
acids,	be er	known	as	DNA	and	RNA.	 
• 	Each	nucleic	acid	is	made	from	just	four	different	nucleo des.	 
• 	RNA	contain	the	bases	adenine,	cytosine,	guanine,	and	uracil	 
• 	DNA	contain	adenine,	cytosine,	guanine,	and	thymine.	 
• Polymeriza on	involves	the	phosphate	and	sugar	groups	of	the	 
nucleo des,	which	become	linked	by	phosphodiester	bonds	 
• primary	role:	act	as	ca...
AC 371 Chapter 5 Learnsmart With Questions And Answers Guaranteed Pass
AC 371 Chapter 5 Learnsmart With 
Questions And Answers Guaranteed Pass 
 
 
Sam traded a parcel of land for a tractor and a car. He had 
purchased the land five years earlier for $16,000. The market 
value of the car and tractor is $20,000. What is the amount of 
gross income resulting from this transaction? 
a. $4,000 
b. $20,000 
c. $0 
d. $16,000 - ANSWER>>>A 
 
Mary has received the following income and fringe benefits 
during the current year: a $73,000 salary; $600 ...
- Judgments
- • 19 pages •
AC 371 Chapter 5 Learnsmart With 
Questions And Answers Guaranteed Pass 
 
 
Sam traded a parcel of land for a tractor and a car. He had 
purchased the land five years earlier for $16,000. The market 
value of the car and tractor is $20,000. What is the amount of 
gross income resulting from this transaction? 
a. $4,000 
b. $20,000 
c. $0 
d. $16,000 - ANSWER>>>A 
 
Mary has received the following income and fringe benefits 
during the current year: a $73,000 salary; $600 ...
ACRP CP WITH DETAILED QUESTIONS AND VERIFIED ANSWERS ALREADY GRADED A
ACRP CP WITH DETAILED QUESTIONS 
AND VERIFIED ANSWERS ALREADY 
GRADED A 
 
 
 
Phase I - ANSWER>>>The clinical trial phase that focuses on 
safety and human pharmacology in healthy volunteers 
 
Who is ultimately responsible for all aspects of the research 
conducted at a site? - ANSWER>>>Principal investigator 
 
Define GCP - ANSWER>>>An international quality standard 
that is provided by ICH E6(R2) describing safety, accuracy of 
trials and credibility ...
- Exam (elaborations)
- • 8 pages •
ACRP CP WITH DETAILED QUESTIONS 
AND VERIFIED ANSWERS ALREADY 
GRADED A 
 
 
 
Phase I - ANSWER>>>The clinical trial phase that focuses on 
safety and human pharmacology in healthy volunteers 
 
Who is ultimately responsible for all aspects of the research 
conducted at a site? - ANSWER>>>Principal investigator 
 
Define GCP - ANSWER>>>An international quality standard 
that is provided by ICH E6(R2) describing safety, accuracy of 
trials and credibility ...
Acute inflammation
Acute inflammation 
 A physiological response to injury by living 
tissue. 
 The response is mounted by the 
microvasculature (meta-arterioles, 
capillaries, venules) 
INJURY INFLAMMATION HEALING 
PROCESS 
 Inflammation is dynamic. 
 -itis implies that the disease is an 
inflammatory response e.g hepatitis, 
nephritis etc. 
 Pneumonitis: Viral induced inflammation of 
the lungs. 
 Pneumonia: Bacterial. 
 Depending on the degree of response ...
- Class notes
- • 23 pages •
Acute inflammation 
 A physiological response to injury by living 
tissue. 
 The response is mounted by the 
microvasculature (meta-arterioles, 
capillaries, venules) 
INJURY INFLAMMATION HEALING 
PROCESS 
 Inflammation is dynamic. 
 -itis implies that the disease is an 
inflammatory response e.g hepatitis, 
nephritis etc. 
 Pneumonitis: Viral induced inflammation of 
the lungs. 
 Pneumonia: Bacterial. 
 Depending on the degree of response ...
Adrenal glands
Adrenal glands 
 •Small, triangular glands loosely 
attached to the kidneys 
 •Divided into two morphologically distinct 
regions- adrenal cortex (outer)- adrenal medulla (inner) 
 
Steroid Hormones 
 • Steroid hormones are produced by the gonads 
and adrenal cortex. 
 • Steroid hormones are made from cholesterol 
in the smooth endoplasmic reticulum and 
mitochondria of endocrine cells.
- Class notes
- • 61 pages •
Adrenal glands 
 •Small, triangular glands loosely 
attached to the kidneys 
 •Divided into two morphologically distinct 
regions- adrenal cortex (outer)- adrenal medulla (inner) 
 
Steroid Hormones 
 • Steroid hormones are produced by the gonads 
and adrenal cortex. 
 • Steroid hormones are made from cholesterol 
in the smooth endoplasmic reticulum and 
mitochondria of endocrine cells.