Aniekvlasma
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Summary Regenerative Medicine
The summary consists of the lectures 
- damage and loss of function of tissue (and regeneration) 
- stem cells 
- molecular organization of cells 
- mechanism of development and regeneration and wound healing 
- extracellular matrix
- Book
- Class notes
- • 49 pages •
The summary consists of the lectures 
- damage and loss of function of tissue (and regeneration) 
- stem cells 
- molecular organization of cells 
- mechanism of development and regeneration and wound healing 
- extracellular matrix
Summary Epigenetics and Gene Editing
This summary consists of: 
1. epigenetic principles underlying gene expression regulation 
2. epigenetic inheritance underlying cell type identity 
3. differentiation principles, in particular neuronal development 
4. genetic and epigenetic editing principles, including CRISPR/Cas platforms 
5. critique and debate current trends and challenges in genetic and epigenetic editing principles on an academic level
- Book
- Class notes
- • 56 pages •
This summary consists of: 
1. epigenetic principles underlying gene expression regulation 
2. epigenetic inheritance underlying cell type identity 
3. differentiation principles, in particular neuronal development 
4. genetic and epigenetic editing principles, including CRISPR/Cas platforms 
5. critique and debate current trends and challenges in genetic and epigenetic editing principles on an academic level
Summary Evolutionary Medicine
This summary covers: 
- A review of evolutionary genetics and dynamics 
- The co-evolution of parasites and hosts 
- Evolution of the immune system 
- Evolution and origin of human infectious diseases 
- Evolution of virulence – why are some infectious diseases fatal and others so mild that they are barely noticed? 
- Evolution of sexually transmitted diseases 
- The evolution of antibacterial and antimicrobial resistance 
- Microbiota and human health 
- Evolutionary processes operating in du...
- Book
- Class notes
- • 29 pages •
This summary covers: 
- A review of evolutionary genetics and dynamics 
- The co-evolution of parasites and hosts 
- Evolution of the immune system 
- Evolution and origin of human infectious diseases 
- Evolution of virulence – why are some infectious diseases fatal and others so mild that they are barely noticed? 
- Evolution of sexually transmitted diseases 
- The evolution of antibacterial and antimicrobial resistance 
- Microbiota and human health 
- Evolutionary processes operating in du...
Summary Neurobiology of Aging
Summary of the lectures given in the course Neurobiology of Aging. Starting with an introduction to the evolution of the brain, then focus on the neurobiology of aging and which diseases are associated with that.
- Class notes
- • 17 pages •
Summary of the lectures given in the course Neurobiology of Aging. Starting with an introduction to the evolution of the brain, then focus on the neurobiology of aging and which diseases are associated with that.
Summary of Immunology
Summary that describes all lectures given in this course, beginning by the history of immunity, the types of cells of the immune system (both innate and adaptive), the production of cytokines, presentation of the antigen to the lymphocytes and diseases correlated to failure of the immune system
- Book
- Class notes
- • 20 pages •
Summary that describes all lectures given in this course, beginning by the history of immunity, the types of cells of the immune system (both innate and adaptive), the production of cytokines, presentation of the antigen to the lymphocytes and diseases correlated to failure of the immune system
Summary of Host- and Microbe Interactions
Summary consists of: 
1. Introduction to microbiome; oral, skin, and gut (composition and function). (El Aidy) 
2. Metagenomic (pathway analysis) and Multi-omics bio-bank cohort analysis (Harmsen) 
3. Early live microbiome (Harmsen + El Aidy) 
4. Diet and Lifestyle and microbiome (El Aidy) 
5. Small intestinal bacteria (link to oral microbiota), Cross feeding among the gut microbes (Harmsen) 
6. Host immunity and microbiome (innate and adaptive) (El Aidy) 
7. Microbiome and gut disorders (IBD)....
- Book
- Class notes
- • 45 pages •
Summary consists of: 
1. Introduction to microbiome; oral, skin, and gut (composition and function). (El Aidy) 
2. Metagenomic (pathway analysis) and Multi-omics bio-bank cohort analysis (Harmsen) 
3. Early live microbiome (Harmsen + El Aidy) 
4. Diet and Lifestyle and microbiome (El Aidy) 
5. Small intestinal bacteria (link to oral microbiota), Cross feeding among the gut microbes (Harmsen) 
6. Host immunity and microbiome (innate and adaptive) (El Aidy) 
7. Microbiome and gut disorders (IBD)....
Endocrinology Summary
The function of the endocrine systems are discussed first (thyroid, parathyroid, pancreatic hormones, adrenal hormones). Next to this, reproduction and the menstrual cycle are explained. Lastly some diseases are explained which are the result of an imbalance of hormone release (e.g. hyper/hypothyroidism)
- Summary
- • 51 pages •
The function of the endocrine systems are discussed first (thyroid, parathyroid, pancreatic hormones, adrenal hormones). Next to this, reproduction and the menstrual cycle are explained. Lastly some diseases are explained which are the result of an imbalance of hormone release (e.g. hyper/hypothyroidism)
Biology and Society: professional Aspects, lectures and practice questions
First all lectures are discussed. For this course we also had to study a Syllabus, the content of the Syllabus is added to this summary. In the end there are some practice questions to test yourself for the exam
- Summary
- • 32 pages •
First all lectures are discussed. For this course we also had to study a Syllabus, the content of the Syllabus is added to this summary. In the end there are some practice questions to test yourself for the exam
Biology of Cancer
Summary that includes all lectures given by Schuringa, Van Vught, Kruyt and de Jong.The topics of the lectures are: carcinogenesis, cancer stem cells, the role of oncogenes and tumor suppressor genes, the large variety of subtypes within hematological and solid tumors, the signaling pathways active in different tumor types, genetic regulation of these molecular pathways (epigenetics, miRNA), DNA damage response, the tumormicroenvironment , the process of metastasis, tumor immunology, therapeutic...
- Book
- Class notes
- • 47 pages •
Summary that includes all lectures given by Schuringa, Van Vught, Kruyt and de Jong.The topics of the lectures are: carcinogenesis, cancer stem cells, the role of oncogenes and tumor suppressor genes, the large variety of subtypes within hematological and solid tumors, the signaling pathways active in different tumor types, genetic regulation of these molecular pathways (epigenetics, miRNA), DNA damage response, the tumormicroenvironment , the process of metastasis, tumor immunology, therapeutic...
Physiology summary
Several items will be addressed like 1) homeostasis and control mechanisms, 2) the autonomic nervous system, 3) the central nervous system, 4) respiration, 5) cardiovascular system, 6) kidneys, blood volume and water balance, 7) muscles, 8) digestive system, 9) regulation of energy balance, 10) endocrine control of growth, stress and metabolism, 11) reproduction and development.
- Book
- Summary
- • 29 pages •
Several items will be addressed like 1) homeostasis and control mechanisms, 2) the autonomic nervous system, 3) the central nervous system, 4) respiration, 5) cardiovascular system, 6) kidneys, blood volume and water balance, 7) muscles, 8) digestive system, 9) regulation of energy balance, 10) endocrine control of growth, stress and metabolism, 11) reproduction and development.