NUR 200 - Med Surg III Exam 3 Study Guide.

NUR 200 - Med Surg III Exam 3 Study Guide/NUR 200 - Med Surg III Exam 3 Study Guide. Immunity Systemic Lupus Erythematosus (SLE) Pathophysiology o Chronic inflammatory, connective tissue disease of unknown origin that affects almost all of the body sytems o Antibodies produced against cellular components (autoantibodies) o Autoantibodies may be triggered by toxins, medications, bacteria, and/or viruses o Autoantibodies ultimately triggers an immune response and leads to local tissue injury o This can lead to widespread inflammation o Autoantibodies production results from hyperactivity of B cells (humoral immune response) because of a disordered T cells function (cellular immune response) o No cure can only control number and frequency of exacerbations o Difficult to diagnosis because of vague early manifestations 3 different types of Lupus