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Bio Chemistry Final Q&A 2022/2023

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Carboxyl Group - Answer - -COO Alpha Carbon - Answer - -C Amino Group - Answer - -NH (+, -) - Answer - -Ionic Bond -Polar and Charged (CH) - Answer - -Non Polar -Hydrophobic -Disrupted by heat (NH, OH) - Answer - -Polar and Uncharged -Hydrogen Bond -Disrupted by PH or salt Dehydration and Hydrolysis - Answer - -Makes a peptide bond -Breaks a peptide bond A peptide bond between two amino acids is made by ______ and ______. - Answer - -C of the carboxyl group and N of amino acid Primary Level - Answer - -Peptide bonds -Backbone Secondary Level - Answer - -Hydrogen bond -Backbone -Salt or PH Tertiary (3D, 1 peptide) - Answer - -Hydrophobic, Hydrogen, Disulfide, Ionic -R Group -Temp, salt, PH, dehydration, reducing agents and aggregation Quaternary (more than 1 peptide) - Answer - -Hydrophobic -R Group -Increased temp Ex: hemoglobin Alzheimer's Disease - Answer - -Aggregate of proteins -Replacing a charged amino acid with a non charged that changes the tertiaru structure -Jelly donut (hydrophbic leaking out)=aggregrate Non Sense Mutation - Answer - -STOP (stop the nonsense) Silent Mutation - Answer - -Does not change amino acid Missence Mutation - Answer - -Changes amino acid (mistake)

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