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2023 HESI PHARMACOLOGY VERSION 2 nurs400

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2023 HESI PHARMACOLOGY VERSION 2 nurs400 (100 QUESTIONS AND ANSWERS WITH RATIONALE)|A GRADED|NEW!!  A client is being treated for hyperthyroidism with propylthiouracil (PTU). The nurse knows that the actionof this drug is to A) decrease the amount of thyroid-stimulating hormone circulating in the blood. B) increase the amount of thyroid-stimulating hormone circulating in the blood. C) increase the amount of T4 and decrease the amount of T3 produced by the thyroid. D) inhibit synthesis of T3 and T4 by the thyroid gland. D) inhibit synthesis of T3 and T4 by the thyroid gland. PTU is an adjunct therapy used to control hyperthyroidism by inhibiting production of thyroid hormones (D). Itis often prescribed in preparation for thyroidectomy or radioactive iodine therapy. Thyroid-stimulating hormone (TSH) is produced by the pituitary gland, and PTU does not affect the pituitary (A and B). PTU inhibitsthe synthesis of all thyroid hormones--both T3 and T4(C).  A client has myxedema, which results from a deficiency of thyroid hormone synthesis in adults. The nurseknows that which medication should be contraindicated for this client? A) Liothyronine (Cytomel) to replace iodine. B) Furosemide (Lasix) for relief of fluid retention. 2023 HESI PHARMACOLOGY VERSION 2 nurs400 (100 QUESTIONS AND ANSWERS WITH RATIONALE)|A GRADED|NEW!! C) Pentobarbital sodium (Nembutal Sodium) for sleep. D) Nitroglycerin (Nitrostat) for angina pain. C) Pentobarbital sodium (Nembutal Sodium) for sleep. Persons with myxedema are dangerously hypersensitive to narcotics, barbiturates (C), and anesthetics. Theydo tolerate liothyronine (Cytomel) (A) and usually receive iodine replacement therapy. These clients are alsosusceptible to heart problems such as angina for which nitroglycerin (Nitrostat) (D) would be indicated, and congestive heart failure for which furosemide (Lasix) (B) would be indicated.  Which change in data indicates to the nurse that the desired effect of the angiotensin II receptorantagonist valsartan (Diovan) has been achieved? A) Dependent edema reduced from +3 to +1. B) Serum HDL increased from 35 to 55 mg/dl. C) Pulse rate reduced from 150 to 90 beats/minute. D) Blood pressure reduced from 160/90 to 130/80. D) Blood pressure reduced from 160/90 to 130/80. 2023 HESI PHARMACOLOGY VERSION 2 nurs400 (100 QUESTIONS AND ANSWERS WITH RATIONALE)|A GRADED|NEW!! Diovan is an angiotensin receptor blocker, prescribed for the treatment of hypertension. The desired effect isa decrease in blood pressure (D). (A, B, and C) do not describe effects of Diovan.  A client is receiving digoxin for the onset of supraventricular tachycardia (SVT). Which laboratory findingsshould the nurse identify that places this client at risk? A) Hypokalemia. B) Hyponatremia. C) Hypercalcemia. D) Low uric acid levels. A) Hypokalemia. Hypokalemia affects myocardial contractility, so (A) places this client at greatest risk for dysrhythmias thatmay be unresponsive to drug therapy. Although an imbalance of serum electrolytes, (B and C), can effect cardiac rhythm, the greatest risk for the client receiving digoxin is (A). (D) does not cause any interactions related to digoxin therapy for supraventricular tachycardia (SVT). 2023 HESI

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