BCMB Exam 3 2024 with 100% correct answers

summarize the overall goal of the pyruvate dehydrogenase complex (PDH) - correct answer an enzyme that catalyzes the transfer of pyruvate to acetyl CoA does low energy charge inhibit or activate the PDH complex? - correct answer activate does phosphorylation activate or inhibit the PDH complex? - correct answer inhibit do high levels of acetyl coA activate or inhibit the PDH complex? - correct answer inhibit at E2 do high levels of NADH activate or inhibit the PDH complex? - correct answer inhibit at E3 Goals of the citric acid cycle? - correct answer 1. to provide electrons for the process of oxidative phosphorylation 2. to provide precursors for biomolecular synthesis What are the net inputs for the citric acid cycle PER glucose molecule - correct answer 2 Acetyl CoA, 2 FAD+, 6 NAD+, 2 ADP, CoA What are the net outputs of the citric acid cycle PER glucose molecule? - correct answer 4 CO2, 2 FADH2, 6 NADH, 2 ATP, 2CoA What are the conditions need for oxaloacetate to be replenished? - correct answer 1. high levels of acetyl CoA 2. a low energy charge Why might a person have elevated concentrations of pyruvate and lactate in the blood? - correct answer The PDH complex is not working and pyruvate is not being broken down so excess pyruvate is turned into lacta