PACKRAT TOP Exam Questions and CORRECT Answers

6 y/o male presents w/ hemarthrosis of the L knee. Coag studies: PT 12.5s (normal12-14 sec), INR 1.0, aPTT 58s (normal 18-28 sec), platelet 430,000/microliter (normal 150,000- 450,000/microliter), & bleeding time 4m (normal 2-12m). Which is the best tx option for this pt? A. Desmopressin acetate B. Corticosteroids C. Vitamin K D. Cryoprecipitate(u) A. Desmopressin acetate is indicated in von Willebrand's disease, which presents with a prolonged bleeding time. (u) B. Corticosteroids are indicated in immune-mediated thrombocytopenia. (u) C. Vitamin K deficiency will prolong the PT greater than the aPTT. Vitamin K supplement is not indicated in this patient. (c) D.Hemophilia A presents with a prolonged aPTT and normal platelet count and function. Hemophilia A is treated with factor VIII concentrate or cryoprecipitate.