N3300 Exam 4 Questions with Correct Answers
Ampicillin Drug Class Correct Answer ✓✓ -penicillin
Ampicillin Use Correct Answer ✓✓ -bacterial infections caused by
susceptible microorganisms
-prophylaxis of infective endocarditis
-broad spec (skin, soft tissue, respiratory, GI, GU)
Ampicillin Serious Side Effects Correct Answer ✓✓ -hypersensitivity
reactions
-dysphagia, seizures, coma
-hepatotoxicity, hypokalemia, hypernatremia
-black box: inadvertant IV admin may result in cardiopulmonary
arrest/death
Ampicillin Adverse Effects Correct Answer ✓✓ -ab pain, diarrhea,
gastritis, nausea, vomiting
-confusion, lethargy, twitching
Ampicillin Contraindications Correct Answer ✓✓ -allergic reactions
(allergic to 1, allergic to whole class)
-caution in neonates (immature kidney function)
-safe in older adults but susceptible to superinfections (renal function)
,Ampicillin Nursing Considerations Correct Answer ✓✓ -often give
concomitantly with aminoglycosides for serious infections
-give on empty stomach oral (1 hr before/2 hr after meal)
-take for full course
-short term use
Cefazolin Drug Class Correct Answer ✓✓ -cephalosporins (1st gen)
Cefazolin Use Correct Answer ✓✓ -parenteral agent frequently used
-surgical prophylaxis and treatment of infections
-bacterial infections, gram + and - depending on generation
Cefazolin Serious Side Effects Correct Answer ✓✓ -hypersensitivity
reactions and superinfections
Cefazolin Adverse Effects Correct Answer ✓✓ -ab pain, diarrhea,
gastritis, nausea, vomiting
Cefazolin Contraindications Correct Answer ✓✓ -previous severe
anaphylactic reaction to penicillin (risk of cross sensitivity)
Cefazolin Nursing Considerations Correct Answer ✓✓ -associated with
decrease in prothrombin activity, monitor those previous stabilized on
anticoagulants
-take full course
,-short term use
-as move down generation, gain gram - and lose + activity
Imipenem/Cilastatin (Primaxin) Drug Class Correct Answer ✓✓ -
carbapenem
Imipenem/Cilastatin (Primaxin) Use Correct Answer ✓✓ -wide range of
bacterial infections (more serious)
-treats infections resistant to other drugs
-polymicrobial, bacterial septicemia, endocarditis
Imipenem/Cilastatin (Primaxin) Serious Side Effects Correct Answer
✓✓ -CNS toxicity seizures
-superinfection
Imipenem/Cilastatin (Primaxin) Adverse Effects Correct Answer ✓✓ -
cross-senstivity and gastric disturbances
-hypersensitivity reactions
-phlebitis at infusion site
Imipenem/Cilastatin (Primaxin) Contraindications Correct Answer ✓✓ -
cross-reactivity in penicillin allergy
-severe shock or atrioventricular block shouldn't receive IM
, Imipenem/Cilastatin (Primaxin) Nursing Considerations Correct Answer
✓✓ -lidocaine can be used to help decrease pain
-want baseline assessment prior
Aztreonam Drug Class Correct Answer ✓✓ -monobactam
Aztreonam Use Correct Answer ✓✓ -infections caused by N.
gonorrhoeae, H. influenzae, enterbacter-klebsiella-serratia species
-infections of urinary tract, skin, and lower respiratory tract
-can cause elevation in hepatic enzymes
Aztreonam Serious Side Effects Correct Answer ✓✓ -C. diff associated
diarrhea and pseudomembranous colitis
Aztreonam Adverse Effects Correct Answer ✓✓ -rash, diarrhea, nausea,
vomiting, localized thrombophlebitis
Aztreonam Nursing Considerations Correct Answer ✓✓ -synergistic
effects between aztreonam and aminoglycosides
Gentamicin Drug Class Correct Answer ✓✓ aminoglycosides
Gentamicin Use Correct Answer ✓✓ - empiric therapy for serious
infections caused by susceptible aerobic gram-negative organisms
Ampicillin Drug Class Correct Answer ✓✓ -penicillin
Ampicillin Use Correct Answer ✓✓ -bacterial infections caused by
susceptible microorganisms
-prophylaxis of infective endocarditis
-broad spec (skin, soft tissue, respiratory, GI, GU)
Ampicillin Serious Side Effects Correct Answer ✓✓ -hypersensitivity
reactions
-dysphagia, seizures, coma
-hepatotoxicity, hypokalemia, hypernatremia
-black box: inadvertant IV admin may result in cardiopulmonary
arrest/death
Ampicillin Adverse Effects Correct Answer ✓✓ -ab pain, diarrhea,
gastritis, nausea, vomiting
-confusion, lethargy, twitching
Ampicillin Contraindications Correct Answer ✓✓ -allergic reactions
(allergic to 1, allergic to whole class)
-caution in neonates (immature kidney function)
-safe in older adults but susceptible to superinfections (renal function)
,Ampicillin Nursing Considerations Correct Answer ✓✓ -often give
concomitantly with aminoglycosides for serious infections
-give on empty stomach oral (1 hr before/2 hr after meal)
-take for full course
-short term use
Cefazolin Drug Class Correct Answer ✓✓ -cephalosporins (1st gen)
Cefazolin Use Correct Answer ✓✓ -parenteral agent frequently used
-surgical prophylaxis and treatment of infections
-bacterial infections, gram + and - depending on generation
Cefazolin Serious Side Effects Correct Answer ✓✓ -hypersensitivity
reactions and superinfections
Cefazolin Adverse Effects Correct Answer ✓✓ -ab pain, diarrhea,
gastritis, nausea, vomiting
Cefazolin Contraindications Correct Answer ✓✓ -previous severe
anaphylactic reaction to penicillin (risk of cross sensitivity)
Cefazolin Nursing Considerations Correct Answer ✓✓ -associated with
decrease in prothrombin activity, monitor those previous stabilized on
anticoagulants
-take full course
,-short term use
-as move down generation, gain gram - and lose + activity
Imipenem/Cilastatin (Primaxin) Drug Class Correct Answer ✓✓ -
carbapenem
Imipenem/Cilastatin (Primaxin) Use Correct Answer ✓✓ -wide range of
bacterial infections (more serious)
-treats infections resistant to other drugs
-polymicrobial, bacterial septicemia, endocarditis
Imipenem/Cilastatin (Primaxin) Serious Side Effects Correct Answer
✓✓ -CNS toxicity seizures
-superinfection
Imipenem/Cilastatin (Primaxin) Adverse Effects Correct Answer ✓✓ -
cross-senstivity and gastric disturbances
-hypersensitivity reactions
-phlebitis at infusion site
Imipenem/Cilastatin (Primaxin) Contraindications Correct Answer ✓✓ -
cross-reactivity in penicillin allergy
-severe shock or atrioventricular block shouldn't receive IM
, Imipenem/Cilastatin (Primaxin) Nursing Considerations Correct Answer
✓✓ -lidocaine can be used to help decrease pain
-want baseline assessment prior
Aztreonam Drug Class Correct Answer ✓✓ -monobactam
Aztreonam Use Correct Answer ✓✓ -infections caused by N.
gonorrhoeae, H. influenzae, enterbacter-klebsiella-serratia species
-infections of urinary tract, skin, and lower respiratory tract
-can cause elevation in hepatic enzymes
Aztreonam Serious Side Effects Correct Answer ✓✓ -C. diff associated
diarrhea and pseudomembranous colitis
Aztreonam Adverse Effects Correct Answer ✓✓ -rash, diarrhea, nausea,
vomiting, localized thrombophlebitis
Aztreonam Nursing Considerations Correct Answer ✓✓ -synergistic
effects between aztreonam and aminoglycosides
Gentamicin Drug Class Correct Answer ✓✓ aminoglycosides
Gentamicin Use Correct Answer ✓✓ - empiric therapy for serious
infections caused by susceptible aerobic gram-negative organisms
