ONS/ONCC Chemotherapy Immunotherapy Certificate Questions with Correct Answers
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Course
Chemotherapy immunotherpy
Institution
Chemotherapy Immunotherpy
The Normal Cell Cycle Correct Ans -The cell cycle refers to the ordered seres of processes of DNA replication and mitosis, or cell division
-Cell nucleus regulates these processes by gathering and processing complexes molecular information
Interphase and Mitotic Phase Correct Ans Cell divis...
ONS/ONCC Chemotherapy Immunotherapy
Certificate Questions with Correct Answers
The Normal Cell Cycle Correct Ans ✓✓ -The cell cycle refers to the
ordered seres of processes of DNA replication and mitosis, or cell
division
-Cell nucleus regulates these processes by gathering and processing
complexes molecular information
Interphase and Mitotic Phase Correct Ans ✓✓ Cell division produces
two identical cells through these two major phases
During interphase: Correct Ans ✓✓ Cell grows and DNA is replicated
through the following three steps:
1: First growth phase (G1 or first gap)
2: Synthesis phase (S phase)
3:Mitotic Phse (M phase)
First Growth Phase (G1 or first gap) Correct Ans ✓✓ -cells increase in
size
-reproduce RNA
,-"quality assurance" test that the cell will be ready to synthesis DNA
-Length of time is variable, can be from hours to days
Synthesis Phase (S phase) Correct Ans ✓✓ -DNA replicates
-Results in the formation of identical pairs of DNA (chromatids)
-which are attached a t the centromere
-lasts 2-10 hours
Mitotic Phase (M phase) Correct Ans ✓✓ -Replicated chromosomes are
aligned, separated, and move into 2 new, identical daughter cells
-takes about 30-60 minutes
Major points of cell regulation are entry and exit from Correct Ans ✓✓ -
G1 checkpoint
-S Phase
-G2 checkpoint
,-M phase
Restriction Point Correct Ans ✓✓ -The transition from the resting phase
into an actively dividing phase (G0-G1) is a point where cellular
transformation can occur
-During this time, cells pass through a transition phase known as a
restriction point
-Extracellular growth factors trigger reentry into G1, and GF are
required to send the cells past the restriction point, or the point of no
return
G0 Phase (resting phase) Correct Ans ✓✓ -After mitosis, cells may
enter back into the G1 phase or go into a resting phase, known as G0
-Most cells in the human body reside in G0
-Exceptions to this are those that are (Resting in G0 phase) Correct Ans
✓✓ -Exceptions to this are those that are metabollically active, such as
-granulocytes
-and the epithelium of the GI tract
, Cell Cycling Time Correct Ans ✓✓ Amount of time from mitosis to
mitosis
Cell cycle video and image Correct Ans ✓✓
http://highered.mheducation.com/sites/0072495855/student_view0/chapt
er2/animation__how_the_cell_cycle_works.html
Check points in the Cell Cycle: Keeping it All Under Control Correct
Ans ✓✓ -The cell cycle is carefully controlled through a series of
checkpoints
-Variation in duplication or distribution of chromosomes during cell
division can alter the genetic information passed on to daughter cells,
leading to cellular dysfunction and disease, such as cancer
-These checkpoints monitor for DNA integrity and control progression
through mitosis
Progression through the cell cycle is controlled through two proteins:
Correct Ans ✓✓ 1. cyclines (D, E, A, B)
2. Cyclin-dependent kinases (CDKs)
-Cyclin-CDK complex allows the cell to progress through each phase of
the cell cycle
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